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Ashkenazi Jewish Genetic Panel (AJGP) - Who Should Be Tested?

Genetic tests can be done for anyone who wants to know whether he or she is a carrier of certain diseases. The Ashkenazi Jewish genetic panel (AJGP) shows the chance of having a child with a disease that is more common among people of Eastern European Jewish heritage. Anyone who is interested in knowing his or her carrier status can ask for the test, but a doctor must order it.

Genetic test results often raise ethical, religious, or legal concerns. You should have genetic counseling before making a decision about testing. Genetic counselors are trained to explain the test and its possible results clearly. A genetic counselor can help you make well-informed decisions.

An AJGP may be recommended for people of Eastern European Jewish heritage, including:

  • Partners of people with diseases on the test panel. For example, if one partner has cystic fibrosis (CF) and the other partner has the CF gene change, a child will have a 50% chance of having CF.
  • Couples planning to have children.
  • Pregnant women (and their partners) who seek prenatal care, whether they have a history of genetic diseases or not.
  • Adults with a positive family history of a disease that is on the test panel.

If only one member of a couple has Ashkenazi Jewish heritage, that person is tested first. If test results show that the person is a carrier of a genetic disease, then his or her partner also should be tested.

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WebMD Medical Reference from Healthwise

Last Updated: March 28, 2012
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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