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Treatment of Newly Diagnosed and Recurrent Childhood Brain Tumors

    The brain is made of different kinds of cells. Childhood brain tumors are grouped and treated based on the type of cell the cancer formed in and where the tumor began growing in the CNS. Some types of tumors are divided into subtypes based on how the tumor looks under a microscope. See Table 1 for a list of tumor types and staging and treatment information for newly diagnosed and recurrent childhood brain tumors.

    Table 1. The Staging and Treatment of Newly Diagnosed or Recurrent Tumors According to Tumor Type or Subtype

    Tumor TypeTumor SubtypeStaging and Treatment of Newly Diagnosed and Recurrent Childhood Brain Tumors
     
    Astrocytomas and Other Tumors of Glial Origin  
    Low-Grade AstrocytomasDiffuse fibrillary astrocytomaSeeChildhood Astrocytomas Treatmentfor information on low-grade astrocytomas.
    Gemistocytic astrocytoma
    Oligoastrocytoma
    Oligodendroglioma
    Pilocytic astrocytoma
    Pilomyxoid astrocytoma
    Pleomorphic xanthoastrocytoma
    Protoplasmic astrocytoma
    Subependymal giant cell astrocytoma
    High-Grade AstrocytomasAnaplastic astrocytomaSeeChildhood Astrocytomas Treatmentfor information on high-grade astrocytomas.
    Anaplastic oligoastrocytoma
    Anaplastic oligodendroglioma
    Giant cell glioblastoma
    Glioblastoma
    Gliomatosis cerebri
    Gliosarcoma
     
    Brain Stem Glioma  
     Diffuse intrinsic pontine gliomasSeeChildhood Brain Stem Glioma Treatment.
    Focal or low-grade brain stem gliomas
     
    Central Nervous System Embryonal Tumors  
    MedulloblastomaAnaplasticSeeChildhood Central Nervous System Embryonal Tumors Treatmentfor information on medulloblastoma, central nervous system primitive neuroectodermal tumors (PNETs), and tumors of the pineal region.
    Classic
    Desmoplastic/nodular
    Large cell
    Medulloblastoma with extensive nodularity
    Central Nervous System Primitive Neuroectodermal Tumors (PNETs)Central nervous system ganglioneuroblastoma
    Central nervous system neuroblastoma
    Ependymoblastoma
    Medulloepithelioma
    Tumors of the Pineal RegionPineal parenchymal tumor of intermediate differentiation
    Pineoblastoma
    Pineocytoma
    Papillary tumor of the pineal region
    Central Nervous System Atypical Teratoid/Rhabdoid Tumor SeeChildhood Central Nervous System Atypical Teratoid/Rhabdoid Tumor Treatment.
     
    Central Nervous System Germ Cell Tumors  
    Germinomas  
    TeratomasImmature teratomas
    Mature teratomas
    Teratomas with malignant transformation
    Non-Germinomatous Germ Cell TumorsChoriocarcinoma
    Embryonal carcinoma
    Mixed germ cell tumors
    Yolk sac tumor
     
    Craniopharyngioma SeeChildhood Craniopharyngioma Treatment.
     
    Ependymoma SeeChildhood Ependymoma Treatment.
     
    Tumors of the Choroid Plexus  

      WebMD Public Information from the National Cancer Institute

      Last Updated: February 25, 2014
      This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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