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Children's Vaccines Health Center

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Human Papillomavirus (HPV) Vaccine: What You Need to Know



These symptoms do not last long and go away on their own.

Life-threatening allergic reactions from vaccines are very rare. If they do occur, it would be within a few minutes to a few hours after the vaccination.

Like all vaccines, HPV vaccine will continue to be monitored for unusual or severe problems.

6. What if there is a severe reaction?

What should I look for?

  • Any unusual condition, such as a high fever or behavior changes. Signs of a serious allergic reaction can include difficulty breathing, hoarseness or wheezing, hives, paleness, weakness, a fast heart beat or dizziness.

What should I do?

  • Call a doctor, or get the person to a doctor right away. 
  • Tell your doctor what happened, the date and time it happened, and when the vaccination was given.  
  • Ask your doctor, nurse, or health department to report the reaction by filing a Vaccine Adverse Event Reporting System (VAERS) form.

Or you can file this report through the VAERS web site at, or by calling 800-822-7967.

 VAERS does not provide medical advice.

7. How can I learn more?

  • Ask your doctor or nurse. They can show you the vaccine package insert or suggest other  sources of information. 
  • Call your local or state health department. 
  • Contact the CDC:

-  Call 800-232-4636 (800-CDC-INFO)

- Visit the CDC’s web site at

WebMD Public Information from the CDC

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