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Vaccines Reduce Number of Meningitis Infections, but for How Long?

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Jan. 9, 2001 -- Bacterial meningitis, an often devastating infection resulting in inflammation of the spinal cord and the fluid surrounding the cord and the brain, can cause death, brain damage, hearing loss, severe learning disabilities, and many other potentially devastating conditions. Infants, adolescents, and young adults are most susceptible to infection.

But parents and others who care for children and teens will be relieved to hear that two recent studies have given a big shot in the arm to meningitis prevention efforts. Last week, the British government announced that an aggressive immunization program using a new vaccine against a particularly virulent form of bacterial meningitis, meningitis C, reduced the number of new meningitis cases in the U.K. by up to 90%. And now Canadian researchers report similar success with a mass immunization campaign (using an older form of the vaccine) in the province of Quebec in 1992-1993.

Unlike the new vaccine used in the U.K., however, the vaccine type still in use in both Canada and in the U.S. appears to protect children and teens for only a few years, and infants under 2 get almost no protection, say Phillipe De Wals, PhD, and colleagues in the Jan. 10 issue of the Journal of the American Medical Association.

"The vaccine seems to be highly effective in adults and children over 15 years of age, but not for a long period. The [effectiveness] seems to last for two years, and there is not much indication of any protection after two years. ... Actually, the vaccine is not at all effective in young children and is of low effectiveness in children between 2 and 14 years," says De Wals, a professor in the department of Community Health Sciences at the University of Sherbrooke in Quebec.

This is in marked contrast to the British experience: Meningitis C infection rates in the U.K. among infants and 15- to 17-year-olds plummeted by 90%. As reported by WebMD U.K., only six babies under the age of 1 in the U.K. contracted meningitis C in 2000, compared with 32 the year before.

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