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Combination Drugs for Cholesterol Lowering

Some people with high cholesterol, other cholesterol problems, or some other medical conditions, achieve the best results with combination drugs -- pills that contain more than one medication. Some examples include:

Advicor: Lovastatin and niacin ( nicotinic acid)

Caduet: Atorvastatin and
amlodipine, a calcium channel blocker

Liptruzet: A
torvastatin and ezetimibe 

Simcor: Simvastatin and niacin (nicotinic acid)

Vytorin: Simvastatin and
ezetimibe, a cholesterol absorption inhibitor




What Are the Side Effects of Cholesterol-Lowering Drugs?

The side effects of cholesterol-lowering drugs may include:

  • Muscle aches*
  • Abnormal liver function
  • Allergic reaction (skin rashes)
  • Heartburn
  • Dizziness
  • Abdominal pain
  • Constipation
  • Decreased sexual desire
  • Flushing with nicotinic acid

*If you have muscle aches, call your doctor immediately. This could be a sign of a life-threatening condition.

Are There Foods or Other Drugs I Should Avoid While Taking Cholesterol-Lowering Medicine?

You should limit grapefruit juice and fresh grapefruit consumption while taking statins, as grapefruit can interfere with the liver's ability to metabolize these medications. Talk with your doctor about your other medications, as it may be appropriate to adjust the dosing of your cholesterol medication depending on interactions.

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