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When you’re trying to lower cholesterol or triglycerides, you may end up in a vitamin shop, facing dozens of supplements. Which ones are worth a try?

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Fish oil. These supplements may help lower triglyceride levels, thanks to omega-3s they have in them like EPA and DHA. 

Just know that getting the amount of omega-3s you need from supplements will add calories to your diet, so watch for weight gain. You’ll need 2-4 grams of fish oil per day. Fish oils are fat, so be sure to check the label to know how many calories you'll add to your total amount. Some people are concerned about high levels of mercury or other pollutants when picking out fish oil supplements. Ask your doctor about safe ones to try.

Psyllium. Fiber is a great cholesterol-buster and part of a healthy diet. Fiber also helps lower triglycerides, especially for people with type 2 diabetes. If you don’t, or can't, get enough fiber from foods -- like vegetables, fruits, and whole grains -- psyllium can fill in the gaps. It’ll whisk away cholesterol, but like other fiber, it can make you need to go to bathroom more often.

Soy protein supplements. Soy can lower overall cholesterol levels and improve your levels of HDL “good” cholesterol, according to studies. Eating soy protein instead of animal protein (like meat and full-fat dairy) can also help lower LDL "bad" cholesterol and total cholesterol levels.

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Coenzyme Q10.  This powerful antioxidant can lower bad LDL cholesterol's ability to stick to the blood vessels of mice. However, scientists say that more research is needed to confirm whether it can work in humans.

So, what about it does work? If you’re taking a statin to lower your cholesterol and having muscle pain as a side effect, there is some proof that coenzyme Q10 can help ease it.

Garlic. Garlic supplements slightly lowered cholesterol levels in a few short studies. But overall, the evidence doesn’t seem to support garlic as an effective way to lower cholesterol.

Niacin. This B vitamin can boost HDL “good" cholesterol and lower LDL “bad” cholesterol and triglycerides -- but only use it if your doctor advises you to. For niacin to work you have to take a lot of it, and that can cause serious side effects. At that point it is more like taking a drug than a non-prescription supplement.

Red yeast rice. This supplement has the same active ingredient found in cholesterol-lowering statin drugs. However, the FDA has classified it as a drug and has banned its sale as a supplement in the U.S., saying it needs more regulation because of side effects. If you find it in a store for sale without a prescription, it may not be the real thing. If you’re ordering online, beware! It can have the same side effects as medications and have negative interactions with other drugs.