Hyperlipoproteinemia Type IV
It is possible that the main title of the report Hyperlipoproteinemia Type IV is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
- Carbohydrate-Induced Hyperlipemia
- Hypercholesterolemia, Type IV
- Hyperlipidemia IV
- Hypertriglyceridemia, Endogenous
Hyperlipoproteinemia Type IV is a not uncommon inherited metabolic disorder that is characterized by increased blood levels of the triglyceride form of fat that makes up very low-density lipids (VLDL). Abnormally high blood levels of triglycerides or cholesterol (another form of blood plasma fat) may be the result of poor dietary habits, genetic causes, or other metabolic disorders or a side effect of certain drugs.
Hyperlipoproteinemia Type IV is one of a family of five types of hyperlipoproteinemia, which is an indicator of a risk of heart disease. Each of types I through IV presents a different profile of blood fat and a different set of associated risks of heart disease.
Hyperlipoproteinemia and hyperlipidemia are synonymous. Both refer to an excess of fatty substances (lipids) in the blood. The condition may also be called hyperlipoproteinemia because the fats are transported through the blood as attachments to specialized proteins. These fat-protein complex molecules are called lipoproteins, among which the better known are HDL (high density lipoprotein, LDL (low density lipoprotein), and VLDL (very low density lipoprotein).
Studies have shown that the risk of heart disease is directly proportional to the blood level of a complex chemical called LDL-cholesterol and inversely proportional to the blood level of HDL-cholesterol. If the blood level of LDL is high, then the risk of heart disease is also high. However, if the blood level of HDL is high, the risk of heart disease is correspondingly low.
Hyperlipoproteinemia Type IV is common and frequently runs in families; i.e. it is genetic in origin. It is characterized by high blood triglyceride levels and obesity, usually with mild diabetes.
For a very brief review of each of the other hyperlipoproteinemias. see the Related Disorders section of this report.
American Heart Association
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