Most Statin Users Won't Have Major Side Effects
However, large review found 9 percent higher risk of developing type 2 diabetes
The researchers also found that the higher the dose, the more likely people were to stop participating in a trial due to side effects.
"Side effects do tend to go up with higher doses," cardiologist Steinbaum said. "You want to use as little medication as possible, and combine the use of statins with lifestyle management. There's no medication that's a quick fix and a cure, but it's worth taking statins if you can manage the side effects."
She added that while simvastatin and pravastatin may have the most favorable side effect profiles, "they tend to be the least potent statins. The statins with the greatest effects tend to have the most side effects," Steinbaum said.
"Not all statins are the same," noted study author Naci. "Our study provides evidence that the side effect profiles of individual statins vary, which should be considered when making prescribing decisions."