The 'Man Cold': Do Guys Really React Differently to Colds?

Medically Reviewed by Melinda Ratini, MS, DO on January 06, 2024
3 min read

When a man gets a cold, everything shuts down. They're on the couch in misery -- unwilling to do anything (even go to the doctor). But a woman with a cold just bucks up and goes on about their day.

Or so the myth of the so-called “man cold” goes.

“If a woman has a viral infection or cold, so to speak, she’ll go on with her day’s activities and maybe mention it to a friend,” says psychology expert William Pollack, PhD, explaining the stereotype. “Men will fuss about it and feel like it’s getting in their way, or be angry or irritable that they have to deal with it.”

Put simply, the “man cold” refers to the idea that men handle colds and the flu worse than women.

But is there any truth to it?

Some experts say men and women may, in fact, respond differently to colds.

“I’ve definitely seen it, but not to such epic proportions as some make it sound,” Pollack says.

The difference is less about gender and more about personality, explains Robert L. Wergin, MD, chair of the American Academy of Family Physicians board of directors.

“I certainly have a group of patients that are very in tune with their bodies and have lots of concerns about their health, he says. “So when they have a cold, they magnify it to some degree.”

These patients, Wergin says, tend to think that their symptoms mean something worse is going on. They might have a minor cold, but they’re worried it’s pneumonia.

“It’s a mix of men and women,” he says.

But does the "man cold" myth have any biological or scientific basis to it?  Some studies say men may have more symptoms than women when they have a cold.

“Regarding colds, there may be some impact of sex,” says Kim Templeton, MD, a surgeon at the University of Kansas Hospital. Templeton has done extensive studies on gender differences in health.

The female sex hormone estrogen slows down how fast a virus multiplies, Templeton says. This may lead to fewer symptoms. The flu virus may not spread as quickly in women because of estrogen and how the female body reacts to it. Studies have not shown if the same thing applies to the cold virus.

What’s more, the part of the brain that controls body temperature is larger in men because of testosterone. This may lead to higher fevers in men vs. women, Templeton says. But the research isn’t clear, she cautions.

But these things may not have much impact.

“The way men and women respond to infectious diseases, there’s not really much of a difference between a male response and a female response,” says Aaron E. Glatt, MD, chairman of the department of medicine at South Nassau Communities Hospital.

“There are slight differences in studies and numbers,” Glatt says. “But practically, there are no significant differences in the immune system between men and women.”

Cultural factors play a large role in the idea of the “man cold,” according to Pollack, author of Real Boys: Rescuing Our Sons from the Myths of Boyhood.

Historically, men were trained to think they needed to be “endlessly capable and never failing,” Pollack explains. “So if we get any illness, we make a big deal out of it because it seems like a big deal. It causes more distress because we’re supposed to be infallible.”

In other words, a man has to think his cold is this close to death, or else they shouldn’t be bothered by it. “But of course he is bothered by it,” Pollack says.

Fortunately, many men are letting go of this way of thinking, Pollack says.

“Everyone gets a cold now and then,” he says.