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Prevent Flu the No. 1 Way: Get Vaccinated

The surest way to avoid influenza is to get vaccinated. Flu shots are designed to match each year’s specific circulating strains. While a flu shot doesn't work 100% of the time, it's still your best bet for avoiding the flu and possibly preventing complications, like pneumonia.

Boosting Immunity With Sleep and Positive Thinking

Getting a good night’s sleep just might bolster your defenses against colds and perhaps flu bugs as well. There’s growing evidence of a link between sleep and a healthy immune system.

A 2009 experiment by researchers at Carnegie Mellon University suggests that the more sleep you get, the better your chances of fighting off respiratory bugs. The scientists recruited 153 healthy men and women who agreed to be quarantined and then have cold viruses injected into their nostrils. Over the following 5 days, those who slept less than 7 hours were nearly three times more likely to come down with colds than those who racked up 8 hours of sleep or more. The researchers also measured what sleep scientists call sleep efficiency, a measure of how deeply people sleep. The better the quality of their sleep, the more likely the people were to fight off colds.

Maintaining a positive outlook may also help bolster immune systems. The same research team reported in 2006 that volunteers with a positive outlook on life -- people who were generally happy, lively, and calm -- were better able to fight off both cold and flu viruses than people who were anxious, hostile, or depressed.