Antiviral medications reduce the severity and shorten the duration of influenza (flu) symptoms by 1 or 1½ days if given within 48 hours of the first symptoms.⁵ These medications are not intended to substitute for getting a flu immunization each year. Rather, antiviral medications are important for controlling outbreaks and preventing the spread of infection, especially in people at high risk for developing flu complications.

The antiviral medications zanamivir and oseltamivir are used to prevent and treat influenza A and B infections. They can reduce the severity and shorten the duration of flu symptoms.⁶ Amantadine and rimantadine have been used to help prevent and treat the flu caused by influenza A (but not influenza B) infection. But for the past few years the U.S. Centers for Disease Control and Prevention (CDC) has advised doctors not to use amantadine or rimantadine to treat or prevent the flu.⁴ These medicines have not worked against most types of the flu virus. It is important to talk with your doctor about the medicine that is best for you.

For more information, see:

Should I take antiviral medicine for the flu?

Medication Choices

Two types of antiviral medications can treat influenza infections:

Amantadine or rimantadine (used to prevent or treat influenza A infections)

Zanamivir or oseltamivir (used to treat and prevent influenza A and B infections)

What To Think About

The effectiveness of antiviral medications can vary from year to year. Some years a medication may not work against the types of influenza virus causing symptoms. Your doctor can help you decide whether antiviral medicines are likely to help you.

Most people do not need antiviral medications. They recover from influenza without developing complications.

However, given how sick most people are when they have the flu, some people may choose to take medication even if they are at low risk for complications.

You cannot prevent the flu or make yourself feel better faster by taking:

• Antibiotics. For more information, see the topic Using Antibiotics Wisely.
• Large doses of vitamins and minerals, such as vitamin C or zinc.
• Herbal remedies, such as echinacea.