Before doctors can prescribe new medications and treatments, they must be shown to be safe and effective. Colorectal cancerclinical trials allow test the effects of new medications on volunteers with colorectal cancer. The researchers follow a strict protocol and use carefully controlled conditions to evaluate the drugs being developed. The evaluation focuses on how well the drug treats colorectal cancer. Researchers also determine its safety and any possible side effects.
Some patients with colorectal cancer are reluctant to take part in clinical trials. One reason is fear of getting no treatment at all. This fear, though, is unwarranted. Patients with colorectal cancer who take part in colorectal cancer trials receive either the most effective therapy available or a treatment that is being evaluated for future use. The cancer drugs being tested may be even more effective than the current colorectal cancer treatment. But a clinical trial is the only way to determine whether they are or not.
For the great majority of people, the major factor that increases a person's risk for colorectal cancer (CRC) is increasing age. Risk increases dramatically after age 50 years; 90% of all CRCs are diagnosed after this age. The history of CRC in a first-degree relative, especially if before the age of 55 years, roughly doubles the risk. Other risk factors are weaker than age and family history. People with inflammatory bowel disease have a much higher risk of CRC. A small percentage (<5%) of CRCs...
This web site was developed by the nonprofit Coalition of Cancer Cooperative Groups. It is an unbiased cancer clinical trial matching and navigation service that enables patients to search for cancer trials based on disease and location.