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Colorectal Cancer Health Center

Medical Reference Related to Colorectal Cancer

  1. Colorectal Cancer Prevention (PDQ®): Prevention - Patient Information [NCI] - nci_ncicdr0000258007-nci-header

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Colorectal Cancer Prevention

  2. Rectal Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage 0 Rectal Cancer

    Stage 0 rectal cancer is the most superficial of all rectal lesions and is limited to the mucosa without invasion of the lamina propria. Because of its superficial nature, surgical and other procedures may be limited. Standard treatment options:Local excision or simple polypectomy.[1]Full-thickness rectal resection by the transanal or transcoccygeal route for large lesions not amenable to local excision.Endocavitary radiation therapy.[2,3,4]Local radiation therapy.[2]Current Clinical TrialsCheck for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage 0 rectal cancer. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.General information about clinical trials is also available from the NCI Web site.References: Bailey HR, Huval WV, Max E, et al.: Local excision of carcinoma of the rectum for cure. Surgery 111 (5): 555-61, 1992. Kodner IJ, Gilley MT, Shemesh EI, et al.: Radiation

  3. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage II Colon Cancer Treatment

    Standard Treatment Options for Stage II Colon CancerSurgeryStandard treatment options for stage II colon cancer include the following:Wide surgical resection and anastomosis.Evidence (laparoscopic techniques):The role of laparoscopic techniques [1,2,3,4] in the treatment of colon cancer was examined in a multicenter, prospective, randomized trial (NCCTG-934653, now closed) comparing laparoscopic-assisted colectomy (LAC) to open colectomy.Three-year recurrence rates and 3-year overall survival (OS) rates were similar in the two groups. (Refer to the Primary Surgical Therapy section in the Treatment Option Overview section of this summary for more information.)The quality-of-life component of this trial has been published and minimal short-term quality-of-life benefits with LAC were reported.[4][Level of evidence: 1iiC]Treatment Options Under Clinical EvaluationAdjuvant chemotherapyThe potential value of adjuvant chemotherapy for patients with stage II colon cancer remains

  4. Colorectal Cancer Prevention (PDQ®): Prevention - Health Professional Information [NCI] - About This PDQ Summary

    PURPOSE OF THIS SUMMARY This PDQ cancer information summary for health professionals provides comprehensive,peer-reviewed,evidence-based information about colorectal cancer prevention. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care decisions. REVIEWERS AND UPDATES This ...

  5. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage III Colon Cancer Treatment

    Stage III colon cancer denotes lymph node involvement. Studies have indicated that the number of lymph nodes involved affects prognosis; patients with one to three involved nodes have a significantly better survival than those with four or more involved nodes.Standard Treatment Options for Stage III Colon CancerStandard treatment options for stage III colon cancer include the following:Surgery.Adjuvant chemotherapy.SurgerySurgery for stage III colon cancer is wide surgical resection and anastomosis.Evidence (laparoscopic techniques):The role of laparoscopic techniques [1,2,3,4] in the treatment of colon cancer was examined in a multicenter, prospective, randomized trial (NCCTG-934653, now closed) comparing laparoscopic-assisted colectomy (LAC) with open colectomy.Three-year recurrence rates and 3-year overall survival (OS) rates were similar in the two groups. (Refer to the Primary Surgical Therapy section in the Treatment Option Overview section of this summary for more

  6. Colorectal Cancer Screening (PDQ®): Screening - Patient Information [NCI] - General Information About Colorectal Cancer

    Colorectal cancer is a disease in which malignant (cancer) cells form in the tissues of the colon or the rectum. The colon and rectum are parts of the body's digestive system. The digestive system removes and processes nutrients (vitamins,minerals,carbohydrates,fats,proteins,and water) from foods and helps pass waste material out of the body. The digestive system is made up of the mouth,...

  7. Rectal Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - General Information About Rectal Cancer

    Rectal cancer is a disease in which malignant (cancer) cells form in the tissues of the rectum. The rectum is part of the body’s digestive system. The digestive system removes and processes nutrients (vitamins,minerals,carbohydrates,fats,proteins,and water) from foods and helps pass waste material out of the body. The digestive system is made up of the esophagus,stomach,and the small ...

  8. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Treatment Option Overview for Colon Cancer

    Table 6. Standard Treatment Options for Stages 0–III Colon CancerStage (TNM Staging Criteria)Standard Treatment OptionsStage 0 Colon CancerSurgeryStage I Colon CancerSurgeryStage II Colon CancerSurgeryStage III Colon CancerSurgery Adjuvant chemotherapyTable 7. Treatment Options for Stage IV and Recurrent Colon CancerStage (TNM Staging Criteria)Treatment OptionsTreatment of Liver MetastasisSurgeryNeoadjuvant chemotherapyLocal ablationAdjuvant chemotherapyIntra-arterial chemotherapyTreatment of Stage IV and Recurrent Colon CancerSurgeryChemotherapy and targeted therapySecond-line chemotherapyPrimary Surgical TherapyStandard treatment for patients with colon cancer has been open surgical resection of the primary and regional lymph nodes for localized disease.The role of laparoscopic techniques [1,2,3,4] in the treatment of colon cancer has been examined in two studies.Evidence (laparoscopic techniques):A multicenter, prospective, randomized, noninferiority trial

  9. Rectal Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - About PDQ

    PDQ IS A COMPREHENSIVE CANCER DATABASE AVAILABLE ON NCI'S WEB SITE. PDQ is the National Cancer Institute's (NCI's) comprehensive cancer information database. Most of the information contained in PDQ is available online at NCI's Web site. PDQ is provided as a service of the NCI. The NCI is part of the National Institutes of Health,the federal government's focal point for biomedical research. .

  10. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage IV and Recurrent Colon Cancer Treatment

    Stage IV colon cancer denotes distant metastatic disease. Treatment of recurrent colon cancer depends on the sites of recurrent disease demonstrable by physical examination and/or radiographic studies. In addition to standard radiographic procedures, radioimmunoscintography may add clinical information that may affect management.[1] Such approaches have not led to improvements in long-term outcome measures such as survival.Treatment Options for Stage IV and Recurrent Colon CancerTreatment options for stage IV and recurrent colon cancer include the following:Surgical resection of locally recurrent cancer.Surgical resection and anastomosis or bypass of obstructing or bleeding primary lesions in selected metastatic cases.Resection of liver metastases in selected metastatic patients (5-year cure rate for resection of solitary or combination metastases exceeds 20%) or ablation in selected

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