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Colorectal Cancer Health Center

Medical Reference Related to Colorectal Cancer

  1. Rectal Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage II Rectal Cancer

    Treatment options:Preoperative chemoradiation with fluorouracil (5-FU) for patients with clinically staged T3 or T4 rectal adenocarcinoma.Total mesorectal excision (TME) with either low anterior resection (LAR) or abdominoperineal resection (APR).Postoperative chemoradiation for patients with stage II or III rectal cancer who did not receive preoperative chemoradiation.Four to six months of 5-FU-based chemotherapy postoperatively.A clinical trial.Prior to the standard use of preoperative chemoradiation for stage II and III rectal cancer, several studies established the benefits of adjuvant combined-modality therapy for surgical stage II and III disease. Intergroup protocol 86-47-51 (MAYO-864751) demonstrated a 10% improvement in overall survival (OS) with the use of continuous-infusion 5-FU (225 mg/m2 /day throughout the entire course of radiation therapy) compared with bolus 5-FU (500 mg/m2 /day for three consecutive days during the first and fifth weeks of radiation).[1][Level of

  2. Colorectal Cancer Screening (PDQ®): Screening - Patient Information [NCI] - Get More Information From NCI

    Call 1-800-4-CANCERFor more information, U.S. residents may call the National Cancer Institute's (NCI's) Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237) Monday through Friday from 8:00 a.m. to 8:00 p.m., Eastern Time. A trained Cancer Information Specialist is available to answer your questions.Chat online The NCI's LiveHelp® online chat service provides Internet users with the ability to chat online with an Information Specialist. The service is available from 8:00 a.m. to 11:00 p.m. Eastern time, Monday through Friday. Information Specialists can help Internet users find information on NCI Web sites and answer questions about cancer. Write to usFor more information from the NCI, please write to this address:NCI Public Inquiries Office9609 Medical Center Dr. Room 2E532 MSC 9760Bethesda, MD 20892-9760Search the NCI Web siteThe NCI Web site provides online access to information on cancer, clinical trials, and other Web sites and organizations that offer support

  3. Colorectal Cancer Screening (PDQ®): Screening - Health Professional Information [NCI] - Questions or Comments About This Summary

    If you have questions or comments about this summary, please send them to Cancer.gov through the Web site's Contact Form. We can respond only to email messages written in English.

  4. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Cellular Classification of Colon Cancer

    Histologic types of colon cancer include the following:Adenocarcinoma (most colon cancers).Mucinous (colloid) adenocarcinoma.Signet ring adenocarcinoma.Scirrhous tumors.Neuroendocrine.[1] Tumors with neuroendocrine differentiation typically have a poorer prognosis than pure adenocarcinoma variants.References: Saclarides TJ, Szeluga D, Staren ED: Neuroendocrine cancers of the colon and rectum. Results of a ten-year experience. Dis Colon Rectum 37 (7): 635-42, 1994.

  5. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Get More Information From NCI

    Call 1-800-4-CANCERFor more information, U.S. residents may call the National Cancer Institute's (NCI's) Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237) Monday through Friday from 8:00 a.m. to 8:00 p.m., Eastern Time. A trained Cancer Information Specialist is available to answer your questions.Chat online The NCI's LiveHelp® online chat service provides Internet users with the ability to chat online with an Information Specialist. The service is available from 8:00 a.m. to 11:00 p.m. Eastern time, Monday through Friday. Information Specialists can help Internet users find information on NCI Web sites and answer questions about cancer. Write to usFor more information from the NCI, please write to this address:NCI Public Inquiries Office9609 Medical Center Dr. Room 2E532 MSC 9760Bethesda, MD 20892-9760Search the NCI Web siteThe NCI Web site provides online access to information on cancer, clinical trials, and other Web sites and organizations that offer support

  6. Colorectal Cancer Prevention (PDQ®): Prevention - Patient Information [NCI] - Colorectal Cancer Prevention

    Avoiding risk factors and increasing protective factors may help prevent cancer.Avoiding cancer risk factors may help prevent certain cancers. Risk factors include smoking, being overweight, and not getting enough exercise. Increasing protective factors such as quitting smoking, eating a healthy diet, and exercising may also help prevent some cancers. Talk to your doctor or other health care professional about how you might lower your risk of cancer.The following risk factors increase the risk of colorectal cancer:AgeThe risk of colorectal cancer increases after age 50. Most cases of colorectal cancer are diagnosed after age 50.Family history of colorectal cancerHaving a parent, brother, sister, or child with colorectal cancer doubles a person's risk of colorectal cancer.Personal historyHaving a personal history of inflammatory bowel disease increases the risk of colorectal cancer. Inherited riskThe risk of colorectal cancer is increased when certain gene changes linked to familial

  7. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage III Colon Cancer Treatment

    Stage III colon cancer denotes lymph node involvement. Studies have indicated that the number of lymph nodes involved affects prognosis; patients with one to three involved nodes have a significantly better survival than those with four or more involved nodes.Standard Treatment Options for Stage III Colon CancerStandard treatment options for stage III colon cancer include the following:Surgery.Adjuvant chemotherapy.SurgerySurgery for stage III colon cancer is wide surgical resection and anastomosis.Evidence (laparoscopic techniques):The role of laparoscopic techniques [1,2,3,4] in the treatment of colon cancer was examined in a multicenter, prospective, randomized trial (NCCTG-934653, now closed) comparing laparoscopic-assisted colectomy (LAC) with open colectomy.Three-year recurrence rates and 3-year overall survival (OS) rates were similar in the two groups. (Refer to the Primary Surgical Therapy section in the Treatment Option Overview section of this summary for more

  8. Rectal Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Stages of Rectal Cancer

    After rectal cancer has been diagnosed, tests are done to find out if cancer cells have spread within the rectum or to other parts of the body.The process used to find out whether cancer has spread within the rectum or to other parts of the body is called staging. The information gathered from the staging process determines the stage of the disease. It is important to know the stage in order to plan treatment. The following tests and procedures may be used in the staging process:Chest x-ray: An x-ray of the organs and bones inside the chest. An x-ray is a type of energy beam that can go through the body and onto film, making a picture of areas inside the body.CT scan (CAT scan): A procedure that makes a series of detailed pictures of areas inside the body, such as the abdomen, pelvis, or chest, taken from different angles. The pictures are made by a computer linked to an x-ray machine. A dye may be injected into a vein or swallowed to help the organs or tissues show up more clearly.

  9. Colorectal Cancer Prevention (PDQ®): Prevention - Patient Information [NCI] - What is prevention?

    Cancer prevention is action taken to lower the chance of getting cancer.

  10. Rectal Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - General Information About Rectal Cancer

    Rectal cancer is a disease in which malignant (cancer) cells form in the tissues of the rectum. The rectum is part of the body’s digestive system. The digestive system removes and processes nutrients (vitamins,minerals,carbohydrates,fats,proteins,and water) from foods and helps pass waste material out of the body. The digestive system is made up of the esophagus,stomach,and the small ...

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