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Colorectal Cancer Health Center

Medical Reference Related to Colorectal Cancer

  1. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - General Information About Colon Cancer

    Related Summaries Note: Other PDQ summaries containing information related to colon cancer include the following: Colorectal Cancer Screening Colorectal Cancer Prevention Genetics of Colorectal Cancer Unusual Cancers of Childhood Treatment (childhood cancer of the colon) Statistics Note: Estimated new cases and deaths from colon cancer in the United States in 2010:[ 1 ] New cases: 102,900 (colon ...

  2. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - To Learn More About Colon Cancer

    For more information from the National Cancer Institute about colon cancer, see the following:Colon and Rectal Cancer Home PageWhat You Need to Know About™ Cancer of the Colon and RectumColorectal Cancer PreventionColorectal Cancer ScreeningTests to Detect Colorectal Cancer and PolypsUnusual Cancers of ChildhoodCryosurgery in Cancer Treatment: Questions and AnswersDrugs Approved for Colon CancerTargeted Cancer TherapiesUnderstanding Cancer Series: Targeted Therapies (Advances in Targeted Therapies)Genetic Testing for Hereditary Cancer SyndromesFor general cancer information and other resources from the National Cancer Institute, see the following:What You Need to Know About™ CancerUnderstanding Cancer Series: CancerCancer StagingChemotherapy and You: Support for People With CancerRadiation Therapy and You: Support for People With CancerCoping with Cancer: Supportive and Palliative CareQuestions to Ask Your Doctor About CancerCancer LibraryInformation For

  3. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Treatment Option Overview

    There are different types of treatment for patients with colon cancer. Different types of treatment are available for patients with colon cancer. Some treatments are standard (the currently used treatment), and some are being tested in clinical trials. A treatment clinical trial is a research study meant to help improve current treatments or obtain information on new treatments for patients with cancer. When clinical trials show that a new treatment is better than the standard treatment, the new treatment may become the standard treatment. Patients may want to think about taking part in a clinical trial. Some clinical trials are open only to patients who have not started treatment. Six types of standard treatment are used:SurgerySurgery (removing the cancer in an operation) is the most common treatment for all stages of colon cancer. A doctor may remove the cancer using one of the following types of surgery:Local excision: If the cancer is found at a very early stage, the doctor may

  4. Colorectal Cancer - General Information About Colorectal Cancer

    Colorectal cancer is a disease in which malignant (cancer) cells form in the tissues of the colon or the rectum. The colon is part of the body's digestive system. The digestive system removes and processes nutrients (vitamins, minerals, carbohydrates, fats, proteins, and water) from foods and helps pass waste material out of the body. The digestive system is made up of the mouth, throat, esophagus, stomach, and the small and large intestines. The first 6 feet of the large intestine are called the large bowel or colon. The last 6 inches are the rectum and the anal canal. The anal canal ends at the anus (the opening of the large intestine to the outside of the body). Anatomy of the lower digestive system, showing the colon and other organs.Cancer that begins in the colon is called colon cancer, and cancer that begins in the rectum is called rectal cancer. Cancer that affects either of these organs may also be called colorectal cancer.See the following PDQ summaries for more information

  5. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Significance

    Colorectal cancer (CRC) is the third most common malignant neoplasm worldwide [1] and the second leading cause of cancer deaths in the United States.[2] It is estimated that there will be 142,820 new cases diagnosed in the United States in 2013 and 50,830 deaths due to this disease. From 2005 to 2009, CRC incidence declined by 4.1% per year among adults aged 50 years and older. However, in adults younger than 50 years, CRC incidence rates have been increasing by 1.1% per year. From 2005 to 2009, mortality from CRC declined by 2.4% per year in men and 3.1% per year in women.[2] The incidence is higher in men than in women. It ranges from 46.1 per 100,000 per year in Hispanic men to 66.9 per 100,000 per year in African American men. In women, it ranges from 31.9 per 100,000 per year in Hispanics to 50.3 per 100,000 per year in African Americans.[3] The age-adjusted mortality rates for men and women are 20.2 per 100,000 per year in men and 14.1 per 100,000 per year in women.[3] About 5%

  6. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage I Colon Cancer Treatment

    Because of its localized nature, stage I colon cancer has a high cure rate.Standard Treatment Options for Stage I Colon CancerSurgeryStandard treatment options for stage I colon cancer include the following:Wide surgical resection and anastomosis.Evidence (laparoscopic techniques):The role of laparoscopic techniques [1,2,3,4] in the treatment of colon cancer was examined in a multicenter, prospective, randomized trial (NCCTG-934653, now closed) comparing laparoscopic-assisted colectomy (LAC) with open colectomy.Three-year recurrence rates and 3-year overall survival rates were similar in the two groups. (Refer to the Primary Surgical Therapy section in the Treatment Option Overview section of this summary for more information.)The quality-of-life component of this trial has been published and minimal short-term quality-of-life benefits with LAC were reported.[5][Level of evidence: 1iiC]Current Clinical TrialsCheck for U.S. clinical trials from NCI's list of cancer clinical trials

  7. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stages of Colon Cancer

    After colon cancer has been diagnosed, tests are done to find out if cancer cells have spread within the colon or to other parts of the body.The process used to find out if cancer has spread within the colon or to other parts of the body is called staging. The information gathered from the staging process determines the stage of the disease. It is important to know the stage in order to plan treatment. The following tests and procedures may be used in the staging process:CT scan (CAT scan): A procedure that makes a series of detailed pictures of areas inside the body, such as the abdomen or chest, taken from different angles. The pictures are made by a computer linked to an x-ray machine. A dye may be injected into a vein or swallowed to help the organs or tissues show up more clearly. This procedure is also called computed tomography, computerized tomography, or computerized axial tomography. MRI (magnetic resonance imaging): A procedure that uses a magnet, radio waves, and a

  8. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - nci_ncicdr0000062687-nci-header

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at or call 1-800-4-CANCER.Colon Cancer Treatment

  9. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage 0 Rectal Cancer

    Stage 0 rectal cancer is the most superficial of all rectal lesions and is limited to the mucosa without invasion of the lamina propria. Because of its superficial nature, surgical and other procedures may be limited. Standard treatment options:Local excision or simple polypectomy.[1]Full-thickness rectal resection by the transanal or transcoccygeal route for large lesions not amenable to local excision.Endocavitary radiation therapy.[2,3,4]Local radiation therapy.[2]Current Clinical TrialsCheck for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage 0 rectal cancer. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.General information about clinical trials is also available from the NCI Web site.References: Bailey HR, Huval WV, Max E, et al.: Local excision of carcinoma of the rectum for cure. Surgery 111 (5): 555-61, 1992. Kodner IJ, Gilley MT, Shemesh EI, et al.: Radiation

  10. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Treatment Option Overview for Colon Cancer

    Table 6. Standard Treatment Options for Stages 0–III Colon CancerStage (TNM Staging Criteria)Standard Treatment OptionsStage 0 Colon CancerSurgeryStage I Colon CancerSurgeryStage II Colon CancerSurgeryStage III Colon CancerSurgery Adjuvant chemotherapyTable 7. Treatment Options for Stage IV and Recurrent Colon CancerStage (TNM Staging Criteria)Treatment OptionsTreatment of Liver MetastasisSurgeryNeoadjuvant chemotherapyLocal ablationAdjuvant chemotherapyIntra-arterial chemotherapyTreatment of Stage IV and Recurrent Colon CancerSurgeryChemotherapy and targeted therapySecond-line chemotherapyPrimary Surgical TherapyStandard treatment for patients with colon cancer has been open surgical resection of the primary and regional lymph nodes for localized disease.The role of laparoscopic techniques [1,2,3,4] in the treatment of colon cancer has been examined in two studies.Evidence (laparoscopic techniques):A multicenter, prospective, randomized, noninferiority trial

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