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    Colorectal Cancer Health Center

    Medical Reference Related to Colorectal Cancer

    1. Rectal Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - To Learn More About Rectal Cancer

      For more information from the National Cancer Institute about rectal cancer, see the following:Colon and Rectal Cancer Home PageWhat You Need to Know About™ Cancer of the Colon and RectumColorectal Cancer PreventionColorectal Cancer ScreeningTests to Detect Colorectal Cancer and PolypsUnusual Cancers of ChildhoodCryosurgery in Cancer Treatment: Questions and AnswersDrugs Approved for Rectal CancerTargeted Cancer TherapiesUnderstanding Cancer Series: Targeted Therapies(Advances in Targeted Therapies)Genetic Testing for Hereditary Cancer SyndromesFor general cancer information and other resources from the National Cancer Institute, see the following:What You Need to Know About™ CancerUnderstanding Cancer Series: CancerCancer StagingChemotherapy and You: Support for People With CancerRadiation Therapy and You: Support for People With CancerCoping with Cancer: Supportive and Palliative CareQuestions to Ask Your Doctor About CancerCancer LibraryInformation For

    2. Rectal Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Colorectal Cancer Screening

      Tests are used to screen for different types of cancer.Some screening tests are used because they have been shown to be helpful both in finding cancers early and decreasing the chance of dying from these cancers. Other tests are used because they have been shown to find cancer in some people; however, it has not been proven in clinical trials that use of these tests will decrease the risk of dying from cancer. Scientists study screening tests to find those with the fewest risks and most benefits. Cancer screening trials also are meant to show whether early detection (finding cancer before it causes symptoms) decreases a person's chance of dying from the disease. For some types of cancer, finding and treating the disease at an early stage may result in a better chance of recovery. Clinical trials that study cancer screening methods are taking place in many parts of the country. Information about ongoing clinical trials is available from the NCI Web site.Studies show that screening for

    3. Colorectal Cancer, Metastatic or Recurrent - Summary of Evidence

      Note: Separate PDQ summaries on Prevention of Colorectal Cancer; Colon Cancer Treatment; and Rectal Cancer Treatment are also available. Based on solid evidence,screening for colorectal cancer reduces colorectal cancer mortality,but there is little evidence that it reduces all cause mortality,possibly because of an observed increase in other causes of death. Table 1: Effect of Screening ...

    4. Rectal Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Evidence of Benefit

      Fecal Occult Blood Test (FOBT)In FOBT testing, a person collects stool samples that are analyzed for the presence of small amounts of blood. Collection details vary somewhat for different tests, but typically involve collection of as many as three different specimens on 3 different days, with small amounts from one specimen smeared by a wooden stick on a card with two windows or otherwise placed in a specimen container.The guaiac test identifies peroxidase-like activity that is characteristic of human and nonhuman hemoglobin. Thus, it will record blood from ingested meat, upper airway bleeding such as epistaxis, upper gastrointestinal (GI) bleeding, as well as colonic lesions.Five controlled clinical trials have been completed or are in progress to evaluate the efficacy of screening utilizing the FOBT. The Swedish trial is a targeted study for individuals aged 60 to 64 years.[1] The

    5. Rectal Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options for Colon Cancer

      Stage 0 (Carcinoma in Situ)Treatment of stage 0 (carcinoma in situ) may include the following types of surgery:Local excision or simple polypectomy.Resection and anastomosis. This is done when the tumor is too large to remove by local excision.Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage 0 colon cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.Stage I Colon CancerTreatment of stage I colon cancer usually includes the following:Resection and anastomosis.Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage I colon cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the

    6. Colorectal Cancer Prevention (PDQ®): Prevention - Health Professional Information [NCI] - Description of the Evidence

      BackgroundIncidence and mortalityColorectal cancer (CRC) is the third most common malignant neoplasm worldwide [1] and the second leading cause of cancer deaths (irrespective of gender) in the United States.[2] It is estimated that there will be 142,820 new cases diagnosed in the United States in 2013 and 50,830 deaths due to this disease.[2] Between 2005 and 2009, CRC incidence rates in the United States declined by 4.1% per year among adults aged 50 years and older.[2] For the past 20 years, the mortality rate has been declining in both men and women. Between 2005 and 2009, the mortality rate declined by 2.4% per year in men and by 3.1% per year in women. In adults younger than 50 years, CRC incidence rates increased by about 1.1% per year.[2] The overall 5-year survival rate is 64%. About 5% of Americans are expected to develop the disease

    7. Rectal Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Option Overview

      There are different types of treatment for patients with colon cancer. Different types of treatment are available for patients with colon cancer. Some treatments are standard (the currently used treatment), and some are being tested in clinical trials. A treatment clinical trial is a research study meant to help improve current treatments or obtain information on new treatments for patients with cancer. When clinical trials show that a new treatment is better than the standard treatment, the new treatment may become the standard treatment. Patients may want to think about taking part in a clinical trial. Some clinical trials are open only to patients who have not started treatment. Six types of standard treatment are used:SurgerySurgery (removing the cancer in an operation) is the most common treatment for all stages of colon cancer. A doctor may remove the cancer using one of the following types of surgery:Local excision: If the cancer is found at a very early stage, the doctor may

    8. Rectal Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Significance

      Colorectal cancer (CRC) is the third most common malignant neoplasm worldwide [1] and the second leading cause of cancer deaths in the United States.[2] It is estimated that there will be 142,820 new cases diagnosed in the United States in 2013 and 50,830 deaths due to this disease. From 2005 to 2009, CRC incidence declined by 4.1% per year among adults aged 50 years and older. However, in adults younger than 50 years, CRC incidence rates have been increasing by 1.1% per year. From 2005 to 2009, mortality from CRC declined by 2.4% per year in men and 3.1% per year in women.[2] The incidence is higher in men than in women. It ranges from 46.1 per 100,000 per year in Hispanic men to 66.9 per 100,000 per year in African American men. In women, it ranges from 31.9 per 100,000 per year in Hispanics to 50.3 per 100,000 per year in African Americans.[3] The age-adjusted mortality rates for men and women are 20.2 per 100,000 per year in men and 14.1 per 100,000 per year in women.[3] About 5%

    9. Rectal Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Recurrent Colon Cancer

      Recurrent colon cancer is cancer that has recurred (come back) after it has been treated. The cancer may come back in the colon or in other parts of the body, such as the liver, lungs, or both.

    10. Colon Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Questions or Comments About This Summary

      If you have questions or comments about this summary, please send them to Cancer.gov through the Web site's Contact Form. We can respond only to email messages written in English.

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