Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started
My Medicine

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Colorectal Cancer Health Center

Font Size

Test May Predict Genetic Colon Cancer

22-Question Quiz Covers Personal and Family History Traits for Lynch Syndrome
WebMD Health News
Reviewed by Louise Chang, MD

Sept. 26, 2006 -- A new quiz may show the odds of getting Lynch syndrome, an inherited form of colon cancer.

The 22-question quiz, described in The Journal of the American Medical Association, focuses on personal and family medical history.

The researchers created the quiz to help screen people at risk for Lynch syndrome.

Lynch syndrome is rare, but it's "the most common hereditary colorectal cancercolorectal cancer syndrome in Western countries, accounting for 2% to 5% of all colorectal cancers," write the researchers.

They included Judith Balmana, MD. She helped develop the new quiz while on staff at Boston's Dana-Farber Cancer Institute and now works in Barcelona, Spain, at the Universitat Autonoma Barcelona.

The quiz is an "objective, easy-to-use tool," write Balmana and colleagues.

Quiz questions include a personal or family history of colon cancer, endometrial cancer, and age at diagnosis.

The test was based on 898 people with a "personal or family history suggestive of Lynch syndrome," the researchers write.

Those patients had been referred for genetic testing to screen for two gene mutations associated with Lynch syndrome. About 14% of them had either of those mutations.

The researchers also gave the test to 1,106 people with Lynch syndrome; approximately 15% of them had the gene mutations.

The quiz "might well be used in the initial assessment of individuals at risk of Lynch syndrome," the researchers write.

Health care workers may also use the quiz "to decide whether to refer the patient for further risk assessment and whether to pursue molecular prescreening," Balmana's team adds.

Several of the researchers (but not Balmana) report having received honoraria or working for the genetics lab that conducted the study's genetic tests.

Today on WebMD

Colorectal cancer cells
The right diagnosis is the most important factor.
man with a doctor
Our health check will steer you in the right direction.
sauteed cherry tomatoes
Fight cancer one plate at a time.
bladder cancer x-ray
Do you know the warning signs?
Colon vs Rectal Cancer
New Colorectal Treatments
can lack of sleep affect your immune system
Cancer Facts Quiz
Virtual Colonoscopy
Picture of the Colon
Vitamin D