New Blood Test May Spot Early Colon Cancer
Study Shows Measuring Levels of CD24 Protein Can Detect Colon Cancer
WebMD News Archive
Testing for Colon Cancer continued...
"CD24 was [dramatically] elevated in colon cancer and adenoma patients,
compared with healthy subjects," Kraus says.
Then, they further tested the accuracy of the CD24 blood test in 73 people:
11 had colon cancer, 24 had adenomas, and 38 showed no signs of colon
The researchers found that the test accurately detected colorectal cancer in
92% of cases; only 8% of colon cancers were missed. It gave false-positive
results to 8% of people who didn't have the cancer.
As for adenomas, the test accurately caught 84% of growths. The
false-positive rate was 11%.
The next step is to validate the findings in studies of larger groups of
people, Kraus says.
The test is expected to cost less than $50, she says.
This isn't the first time researchers have reported they're a step closer to
developing a blood test for colon cancer. Just last year, two teams of European
investigators said they had developed tests that look for genetic fingerprints
of tumor growth and spread in the blood, for example.
Which tests will eventually make it out of the lab and into the clinic is
still anyone's guess, doctors concede.
"People are putting a lot of thought into developing blood tests that are
highly accurate and can detect colon cancer at an early stage," says Robert P.
Sticca, MD, of the University of North Dakota School of Medicine and Health
Sciences and moderator of a news briefing.
"The research is very preliminary, but [if it pans out], it will be a very
useful tool given how common colon cancer is," he tells WebMD.