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Anal Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Recurrent Anal Cancer

Local recurrences and/or persistent disease after treatment with radiation therapy and chemotherapy or surgery as the primary treatment may be controlled by using the alternate treatment (surgical resection after radiation and vice versa).[1] Clinical trials are exploring the use of radiation therapy with chemotherapy and/or radiosensitizers to improve local control.

Current Clinical Trials

Recommended Related to Colorectal Cancer

Stage IV and Recurrent Rectal Cancer

Treatment options for local control: Resection of locally recurrent rectal cancer may be curative in selected patients.[1] Palliative surgical resection with either low-anterior resection (LAR) or abdominoperineal resection (APR).[1] Palliative radiation therapy.[2,3] Palliative chemotherapy.[4,5,6,7,8,9,10] Palliative chemoradiation.[11,12] Chemotherapy alone for local control. Palliative, endoscopic-placed stents to relieve obstruction.[13] Treatment options...

Read the Stage IV and Recurrent Rectal Cancer article > >

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with recurrent anal cancer. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.

General information about clinical trials is also available from the NCI Web site.

References:

  1. Longo WE, Vernava AM 3rd, Wade TP, et al.: Recurrent squamous cell carcinoma of the anal canal. Predictors of initial treatment failure and results of salvage therapy. Ann Surg 220 (1): 40-9, 1994.
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WebMD Public Information from the National Cancer Institute

Last Updated: February 25, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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