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Colon Cancer Genetic Testing - How Accurate Is the Test?

Although these blood tests are highly reliable, no test is 100% accurate. The test cannot tell you when or whether you will develop colon cancer. Testing negative for an inherited colon cancer gene does not mean you will never get colon cancer. It means your risk of colon cancer is about the same as that of the average person.

There are many different genetic mutations that can lead to FAP or HNPCC. Genetic testing does not find all of them. Because of this, a person may have a normal genetic test but still have an increased chance of having an inherited colon cancer.

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Description of the Evidence

Background Incidence and mortality Colorectal cancer (CRC) is the third most common malignant neoplasm worldwide [1] and the second leading cause of cancer deaths (irrespective of gender) in the United States.[2] It is estimated that there will be 142,820 new cases diagnosed in the United States in 2013 and 50,830 deaths due to this disease.[2] Between 2005 and 2009, CRC incidence rates in the United States declined by 4.1% per year among adults aged 50 years and older.[2] For the past...

Read the Description of the Evidence article > >

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Medical Reference from Healthwise

    Last Updated: August 27, 2012
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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