A prospective cohort study examined the use of aspirin after a colorectal cancer diagnosis. Regular users of aspirin after a diagnosis of colorectal cancer experienced an HR of colon cancer-specific survival of 0.71 (95% CI, 0.65–0.97) and an OS of 0.79 (95% CI, 0.65–0.97).[Level of evidence: 3iiA] One study evaluated 964 patients with rectal or colon cancer from the Nurse's Health Study and the Health Professional Follow-up Study. Among patients with PI3K-mutant colorectal cancer, regular use of aspirin was associated with an HR for OS of 0.54 (95% CI, 0.31–0.94; P = .01)[Level of evidence: 3iiiA]
Other PDQ summaries containing information related to colon cancer include the following:
Colorectal Cancer Prevention
Colorectal Cancer Screening
Genetics of Colorectal Cancer
Unusual Cancers of Childhood Treatment (childhood cancer of the colon)
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May 28, 2015
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