Skip to content

Colorectal Cancer Health Center

Font Size

Rectal Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Cellular Classification and Pathology of Rectal Cancer

The World Health Organization (WHO) classification of tumors of the colon and rectum include the following:[1]

Epithelial Tumors

Recommended Related to Colorectal Cancer

Colorectal Cancer: Finding Help

Want a second opinion or looking for a doctor that specializes in treating colon cancer? WebMD’s Physician Directory can help you find an oncologist in your area. Tool: Find a Doctor Who Specializes in Colon Cancer  

Read the Colorectal Cancer: Finding Help article > >

Adenoma

  • Tubular.
  • Villous.
  • Tubulovillous.
  • Serrated.

Intraepithelial neoplasia (dysplasia) associated with chronic inflammatory diseases

  • Low-grade glandular intraepithelial neoplasia.
  • High-grade glandular intraepithelial neoplasia.

Carcinoma

  • Adenocarcinoma.
  • Mucinous adenocarcinoma.
  • Signet-ring cell carcinoma.
  • Small cell carcinoma.
  • Adenosquamous carcinoma.
  • Medullary carcinoma.
  • Undifferentiated carcinoma.

Carcinoid (well-differentiated neuroendocrine neoplasm)

  • Enterochromaffin (EC)-cell, serotonin-producing neoplasm.
  • L-cell, glucagon-like peptide and pancreatic polypeptide/peptide YY (PYY)-producing tumor.
  • Others.

Mixed carcinoma-adenocarcinoma

  • Others.

Nonepithelial Tumors

  • Lipoma.
  • Leiomyoma.
  • Gastrointestinal stromal tumor.
  • Leiomyosarcoma.
  • Angiosarcoma.
  • Kaposi sarcoma.
  • Melanoma.
  • Others.

Malignant lymphomas

Adenocarcinomas account for the vast majority of rectal cancers. Other histologic types of colorectal cancer account for an estimated 2% to 5% of colorectal tumors.[2]

References:

  1. Hamilton SR, Aaltonen LA: Pathology and Genetics of Tumours of the Digestive System. Lyon, France: International Agency for Research on Cancer, 2000.
  2. Kang H, O'Connell JB, Leonardi MJ, et al.: Rare tumors of the colon and rectum: a national review. Int J Colorectal Dis 22 (2): 183-9, 2007.
1

WebMD Public Information from the National Cancer Institute

Last Updated: February 25, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
Next Article:

Today on WebMD

Colorectal cancer cells
The right diagnosis is the most important factor.
man with a doctor
Our health check will steer you in the right direction.
 
sauteed cherry tomatoes
Fight cancer one plate at a time.
bladder cancer x-ray
Do you know the warning signs?
 
bread
ARTICLE
Colon vs Rectal Cancer
VIDEO
 
New Colorectal Treatments
VIDEO
can lack of sleep affect your immune system
FEATURE
 
Cancer Facts Quiz
QUIZ
Virtual Colonoscopy
VIDEO
 
Picture of the Colon
ANATOMY
Vitamin D
SLIDESHOW
 

WebMD Special Sections