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    Rectal Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options by Stage

    Stage 0 (Carcinoma in Situ)

    Treatment of stage 0 may include the following:

    Recommended Related to Colorectal Cancer

    What Is Colorectal Cancer?

    Colorectal cancer is the third most common cancer in the U.S., not including skin cancers. It affects about one in every 20 people. There are about 132,000 new cases each year. It’s also called colon cancer because it affects the colon or rectum. These are both part of the large intestine, which is part of the digestive system. It absorbs water and nutrients from food after it’s moved through the stomach and small intestine. The body’s waste matter (stool) is stored in the colon before moving...

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    • Simple polypectomy.
    • Local excision.
    • Resection (when the tumor is too large to remove by local excision).
    • Internal or external radiation therapy.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage 0 rectal cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

    Stage I Rectal Cancer

    Treatment of stage I rectal cancer may include the following:

    • Local excision.
    • Resection.
    • Resection with radiation therapy and chemotherapy before or after surgery.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage I rectal cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

    Stage II Rectal Cancer

    Treatment of stage II rectal cancer may include the following:

    • Resection plus a combination of chemotherapy and radiation therapy before or after surgery.
    • Resection with or without chemotherapy after surgery.
    • A clinical trial of a new treatment.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage II rectal cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

    Stage III Rectal Cancer

    Treatment of stage III rectal cancer may include the following:

    • Resection plus a combination of chemotherapy and radiation therapy before or after surgery.
    • Resection with or without chemotherapy after surgery.
    • A clinical trial of a new treatment.
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