How Does ENBREL Work?

ENBREL is a type of protein called a tumor necrosis factor (TNF) blocker that blocks the action of a substance your body makes called TNF. Tumor necrosis factor is made by your body's immune system. People with immune diseases such as plaque psoriasis or psoriatic arthritis have too much TNF in their bodies.

Proven Approach

Because ENBREL suppresses the immune system, it may lower your body's ability to fight infection. Be sure to read the important Product Information and talk to your dermatologist.

• Nearly half the patients saw a significant improvement in their plaque psoriasis within 3 months of using ENBREL.
• Overall, 3 out of 4 patients saw improvement.
• ENBREL can work fast; many patients saw improvement within 2 months.
• ENBREL has been shown to work month after month

Your results may vary.

Extensive Experience

• ENBREL has over 15 years of collective clinical experience.
• ENBREL has been used by more than 460,000 patients worldwide across uses.

Established Safety Profile

The safety profile for ENBREL during clinical trials showed:

• Rates of serious adverse events were comparable to control patients in rheumatoid arthritis, psoriatic arthritis, and plaque psoriasis clinical trials.
• The most common adverse events reported were injection site reactions, infections, and headache.
• Routine laboratory monitoring specific for ENBREL therapy is not required; however, careful medical management and supervision of patients are recommended. Tell your doctor if you are prone to infection or have had hepatitis B.

Please see important Product Information below and Full Prescribing Information.