Eye on AMD™ — On your side against MACULAR DEGENERATION

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How LUCENTIS Works

LUCENTIS^® (ranibizumab injection) is a biologic treatment specifically developed for use in the eye. LUCENTIS is formulated under very strict sterile guidelines to help ensure quality and safety. LUCENTIS has been tested in more than a thousand patients in clinical studies, and has been shown to improve or maintain vision in patients with wet AMD.

There are certain proteins that are thought to play a big role in causing wet AMD. Some of these proteins are called VEGF or VEGF-A. LUCENTIS is a treatment that targets the protein VEGF-A, preventing it from causing more damage to your eye.

Wet AMD is caused by new blood vessels growing and leaking fluid in the macula. LUCENTIS is designed to block abnormal blood vessel growth and leakage.

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Who is LUCENTIS for?

LUCENTIS^® (ranibizumab injection) is a prescription medicine for the treatment of patients with wet age-related macular degeneration (AMD).

What important safety information should I know about LUCENTIS?

Like any prescription medication, LUCENTIS is not for everyone. You should not use LUCENTIS if you have an infection in or around the eye.

Like other injections given into the eye, serious eye infection (endophthalmitis) and detached retina have occurred with LUCENTIS. Increases in eye pressure have been seen within 1 hour of an injection. Your eye doctor should monitor your eye pressure and eye health during the week after the injection. If your eye becomes red, sensitive to light, painful, or has a change in vision, you should seek immediate care from your eye doctor.

Although uncommon, conditions associated with eye- and non–eye-related blood clots (arterial thromboembolic events) may occur.

Serious side effects related to the injection procedure were rare. These included serious eye infection, detached retina, and cataract. Other uncommon serious side effects included inflammation inside the eye and increased eye pressure.

The most common eye-related side effects were red eye, eye pain, small specks in vision, the feeling that something is in your eye, and increased tears. The most common non-eye-related side effects were high blood pressure, nose and throat infection, and headache.

LUCENTIS is for Prescription use only. Individual results with LUCENTIS may vary. Please see LUCENTIS full Prescribing Information. For more information visit www.LUCENTIS.com.