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10 Questions to Ask Your Doctor About Treatment-Resistant Depression

8. Should I consider experimental treatments?

If standard treatments haven't worked, you could consider enrolling in a clinical trial of an experimental treatment. These are approaches or medications being studied in clinical trials, but not yet approved by the FDA as depression treatments. Ask your doctor if you might be a good candidate for a clinical trial. Information about research treatment studies for depression can be found at

9. What changes do I need to make to my lifestyle?

There are many things that you can do on your own to support your treatment and potentially ease your symptoms. Ask your health care provider for recommendations on physical activity, sleep habits, and diet.

10. What should I do in an emergency?

You and your doctor should have an explicit plan for crises. If you are ever in danger of hurting yourself or others, you -- and your family -- need to know what steps to take.


WebMD Medical Reference

Reviewed by Joseph Goldberg, MD on June 25, 2013

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