Skip to content
My WebMD Sign In, Sign Up

Depression Health Center

Font Size

Alcohol and Depression

Are Genes or Lifestyle Factors Responsible for the Link Between Alcohol Use and Depression?

It's not always clear for a given individual when depression triggers alcohol abuse or vice versa. But  both conditions may  share common triggers. Studies of twins have shown that the same factors that contribute to heavy drinking in families also contribute to the risk for major depression.

Researchers have been looking for  common  genes that might lie behind both conditions. They have pinpointed at least one -- a variant of the gene CHRM2 -- that is involved in several important brain functions, including memory and attention. Variations in this gene might put people at risk for both alcohol misuse and depression.

A person's home and social environment also can play a  role in determining whether that person will develop both depression and a drinking problem. Children who have been abused or who were raised in poverty appear to be more likely to develop both conditions.


Alcohol and Depression: What to Do

It probably won't hurt to have a glass of wine or beer once in awhile for social reasons unless you have a health problem that prevents you from drinking. But if you're misusing alcohol on a regular basis as a coping mechanism, you have a more serious problem.

Drinking will only worsen the depression you already feel. People who are depressed and who abuse alcohol have more frequent and severe episodes of depression, and are more likely to think about committing suicide. Heavy alcohol use also can make medicines for depression work less effectively.

Alcohol abuse and depression are both serious problems that you shouldn't ignore. If you think you have a problem with alcohol, talk to your doctor or psychologist, or get help from Alcoholics Anonymous (AA) or another alcohol treatment center in your area. Also talk to your doctor or another health care professional about getting help for depression. There is evidence that taking antidepressants may help relieve depression. And a number of other medicines can directly help reduce alcohol cravings and counter the desire to drink heavily.


WebMD Medical Reference

Reviewed by Joseph Goldberg, MD on August 31, 2014

Today on WebMD

Differences between feeling depressed or blue.
depressed man
How well are you managing your symptoms?
depressed man sitting on hallway floor
Learn the truth about this serious illness.
Sad woman looking out of the window
Tips to stay the treatment course.
Woman taking pill
Woman jogging outside
man screaming
woman standing behind curtains
Pet scan depression
antidepressants slideshow
pill bottle
Winding path