Depression Health Center
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Antidepressants: Best for Severe Depression?
Some antidepressants may work best for those with very severe depression while providing little or no benefit for those with mild, moderate, or severe depression.
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Understanding Depression - Symptoms
What Are the Symptoms of Depression?
For major depression, you may experience five or more of the following for at least a two-week period:
- Persistent sadness, pessimism
- Feelings of guilt, worthlessness, helplessness or hopelessness
- Loss of interest or pleasure in usual activities, including sex
- Difficulty concentrating and complaints of poor memory
- Worsening of co-existing chronic disease, such as rheumatoid arthritis or diabetes
- Insomnia or oversleeping
- Weight gain or loss
- Fatigue, lack of energy
- Anxiety, agitation, irritability
- Thoughts of suicide or death
- Slow speech; slow movements
- Headache, stomachache, and digestive problems
Important Safety Information
Vimpat (lacosamide) is a medicine that is used with other medicines to treat partial onset seizures in patients 17 years of age and older with epilepsy. Vimpat is generally well-tolerated, but may not be for everyone. Ask your doctor if Vimpat is right for you. Antiepileptic drugs, including Vimpat, may cause suicidal thoughts or actions in a very small number of people, about 1 in 500. Call your healthcare provider right away if you have new or worsening symptoms of depression, any unusual changes in mood or behavior, or suicidal thoughts, behavior, or thoughts about self harm that you have never had before or may be worse than before. Please see additional patient information in the Medication Guide at the end of the full prescribing information. This information does not take the place of talking with your healthcare provider about your condition or your treatment. Please see additional Patient Safety Information