The Food and Drug Administration sees no difference between brand-name and generic medications for depression. Most psychiatrists readily prescribe generics as effective copies of the original.
That said, it is not at all rare for patients who switch to a generic from a brand-name medication to experience a difference. Sometimes they feel a return of the old sadness, anxiety, and helplessness that the antidepressant helped to lift. Other times, they get an unusual jolt of the same side effects that...
Which comes first? And how can you untangle the link between depression and weight -- especially if depression has sapped you of your energy to make changes? Here's what experts say you need to know.
Depression and Weight Gain
A March 2010 review of 15 studies, published in the Archives of General Psychiatry, linked obesity to a greater risk of developing depression - and vice versa.
But do people gain weight because they are depressed? Or do they become depressed because of the excess pounds they are carrying? No one knows.
“It’s a chicken and the egg phenomenon,” says psychologist Leslie Heinberg, PhD, who directs the Bariatric and Metabolic Institute at the Cleveland Clinic. “But we do know that depression has lots of symptoms that can worsen obesity - appetite disturbances, lack of energy, lack of motivation to do things.”
In 2009, researchers at the University of Alabama at Birmingham reported that depressed people tend to gain weight faster than people who aren't depressed.
Depression, of course, comes with its own set of risk factors, including suicide, social isolation, drug and alcohol addiction, and anxiety.
Whichever comes first - depression or overweight/obesity - it is a very unhealthy combination. Often, it is a self-reinforcing combo as well.
Eating Yourself Blue
“Some foods, especially foods with high sugar and/or fat content, make you feel better, if only briefly,” says psychiatrist James Gordon, MD, author of Unstuck: Your Guide to the Seven-Stage Journey out of Depression.
“That good feeling makes you want to eat more, which in turn makes you feel bad about yourself,” Gordon says. “That leads to deeper depression, and more eating, and greater amounts of weight gain. It’s a vicious cycle.”
Getting out of that cycle can be a real challenge.