The following drugs have been reported to cause depression in some patients. Elderly people are particularly at risk.
Isotretinoin (Sotret, Claravis): This drug treats severe acne.
Anticonvulsants: Anticonvulsants are used to control epileptic seizures, examples include Ethosuximide (Zarontin) and Methsuximide (Celontin).
Barbiturates: These are a group of central nervous system depressants that slow down brain function. These medicines have been used to treat anxiety and to prevent epileptic seizures. They are commonly abused; examples are phenobarbital and secobarbital.
Benzodiazepines: This group of central nervous system depressants is often used to treat anxiety and insomnia and to relax muscles; examples include alprazolam (Xanax), clonazepam (Klonopin), chlordiazepoxide (Librium), diazepam (Valium), flurazepam, lorazepam (Ativan), and triazolam (Halcion).
NuvaRing with ehinyl estradiol/etonogestrel: This is a medicine used for birth control.
Opioids: This group of narcotics is used to relieve moderate to severe pain. These drugs have a high potential for abuse and addiction; examples include codeine, morphine, aspirin/oxycodone (Percodan), meperidine (Demerol), and oxycodone (OxyContin).
What Should I Do If I Think My Medicine Causes Depression or Mania?
Be sure to discuss with your doctor any concerns you may have about how a medicine might be affecting your mood. When a medicine does produce symptoms of mania or depression, your doctor may recommend discontinuing the drug or reducing the dosage (if possible). If this is not possible, your doctor may treat the manic or depressive symptoms with other drugs.