Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Depression Health Center

Font Size

FDA Reviews Adult Antidepressant-Suicide Link

Final Word May Not Come for a Year

WebMD Health News

July 1, 2005 -- The FDA has issued a public health advisory regarding data linking the possibility of an increased risk of suicidal behavior in adults taking antidepressants.

The FDA says it is reviewing recent scientific evidence showing a possible link. It is releasing this information now to update patients and health care providers with the latest information on this subject.

In October 2004, federal health officials ordered makers of antidepressants to use new warningsnew warnings alerting doctors and patients that the medications increase the risk of suicidal thoughts and behaviors in children and adolescents who take them.

Even before the publication of these recent reports, the FDA says it had already begun the process of reviewing available data to determine whether there is an increased risk of suicidal behavior in adults taking antidepressants.

The agency has asked manufacturers of these drugs to provide information from their studies in much the same way they approached evaluation of the risk of suicidal behavior in children taking antidepressants.

The review will involve hundreds of studies and may take more than a year to complete, it says.

In the meantime, the FDA is advising doctors and patients to be aware of the following:

  • Adults being treated with antidepressant medicines, particularly those being treated for depression, should be watched closely for worsening of depression and for increased suicidal thinking or behavior.
  • Close observation of adults may be especially important when antidepressant medications are started for the first time or when doses for the specific drugs prescribed have been changed.
  • Adults whose symptoms worsen while being treated with antidepressants, including an increase in suicidal thinking or behavior, should be evaluated by their health care professional.

These recommendations are consistent with warnings already present in approved labeling for antidepressants used by adults.

Today on WebMD

Differences between feeling depressed and feeling blue.
jk rowling
Famous people who've struggled with persistent sadness.
depressed man sitting on hallway floor
Learn the truth about this serious illness.
Sad woman looking out of the window
Tips to stay the treatment course.
unhappy teen boy
Health Check
jk rowling
Pills with smiley faces
Teen girl huddled outside house
Depressed man sitting in hospital hallway
antidepressants slideshow
pill bottle
Winding path