Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Depression Health Center

Font Size

Wellbutrin XL Goes Generic

Generic Version of Popular Antidepressant Equivalent to Brand, FDA Says
WebMD Health News

Dec. 15, 2006 -- The FDA has approved the first generic version of the antidepressant Wellbutrin XL (bupropion).

In 2005, Wellbutrin XL -- the latest version of Wellbutrin -- was the 21st highest-selling brand-name drug in the U.S, with sales totaling more than $1.3 million, according to the online magazine Drug Topics, the FDA notes.

The benefit to consumers of FDA's generic drug approval is significant because generic drug products, which are used to fill more than 50% of all prescriptions, often cost a fraction of the price of the brand-name drug.

"Bupropion hydrochloride is a widely-used antidepressant, and its generic version can bring significant savings to the millions of Americans with depression," says Gary J. Buehler, RPh, who directs the FDA's Office of Generic Drugs.

"This approval is another example of our agency's efforts to increase access to safe and effective generic alternatives as soon as the law permits," says Buehler in an FDA news release.

The FDA assures consumers and health professionals that an approved generic drug is as safe and effective as a brand-name drug.

The same thorough and rigorously scientific review standards of safety, efficacy, and quality are applied to generic drugs as are applied to brand drugs, according to the FDA.

Generic bupropion extended-release tablets will be sold in two doses: 150 milligrams and 300 milligrams.

The generic tablets are made by Anchen Pharmaceuticals of Irvine, Calif.

Wellbutrin XL is made by GlaxoSmithKline, a WebMD sponsor.

Today on WebMD

Differences between feeling depressed and feeling blue.
jk rowling
Famous people who've struggled with persistent sadness.
depressed man sitting on hallway floor
Learn the truth about this serious illness.
Sad woman looking out of the window
Tips to stay the treatment course.
unhappy teen boy
Health Check
jk rowling
Pills with smiley faces
Teen girl huddled outside house
Depressed man sitting in hospital hallway
antidepressants slideshow
pill bottle
Winding path