‘Depression Gene’ Linked to Response to Stress
Study Shows Gene Plays Role in the Ways People React to Stressful Events
Gene Testing Not Advised continued...
George Tesar, MD, a psychiatrist at the Cleveland Clinic in Ohio, says this genetic variation “is not a cause of depression, but a factor that increases risk of depression in certain individuals.”
It is not a given that if you have this gene, you will develop depression when you experience a stressful situation, he says.
“This article resurrects [the depression gene,] in a fashion, but it never died,” Tesar says. “People still stand by this as a variable.”
When this gene was first discovered in 2003, people in the field wanted it to be the variable to help guide clinical decision making.
It is not the variable, but a variable, Tesar says.
Rudolf Uher, PhD, a clinical lecturer at the Institute of Psychiatry in London, says in a news release that the new study “gives a very clear answer: the 'short' variant of the serotonin transporter does make people more sensitive to the effects of adversity."