March 15, 2011 -- Children who live with depressed moms are at high risk for depression, but successful treatment of the mother greatly improves the prospects for her child, a study shows.
The study followed 80 depressed mothers and their children over time. It showed that depression symptoms, behavioral problems, and other signs of distress among children tended to correspond with the mothers’ response to treatment.
The women and children were participants in a large trial conducted by the National Institute of Mental Health (NIMH) designed to assess the impact of trying different treatment approaches when initial treatments fail.
“Treatment of depression is trial and error, but many patients give up very early and decide they can’t be helped,” Columbia University professor of epidemiology and psychiatry Myrna M. Weissman, PhD, tells WebMD. “This study showed that improvement is possible even after several unsuccessful tries, and that successful treatment of the parent has a long-lasting impact on the child.”
The study did not included fathers, but Weissman says the findings can probably be extrapolated to depressed dads.
About a third of the children enrolled in the larger NIMH study had a current psychiatric disorder and half had a history of such disorders when their mothers started treatment.
Children were assessed at study entry for psychiatric symptoms as well as behavioral problems and functional issues. They were followed, along with their mothers, throughout the two-year study.
The mothers all had major depression when they entered the study with no history of bipolar disorder or schizophrenia. All were initially treated with the antidepressantCelexa, followed by other drug treatments, behavioral therapy, or a combination of behavioral therapy and drugs if depression symptoms did not improve.
When the mothers responded to treatment within three months, their children were most likely to experience improvements in overall psychosocial functioning both at home and at school for at least a year after maternal remission.
Long-term improvements were also seen in children whose mothers took up to a year to respond to treatments. But the children of mothers who remained depressed over the two-year study showed no improvement in symptoms and an increase in disruptive behaviors.
“Remission of mothers’ depression, regardless of its timing, appears to be related to decreases in problem behaviors and symptoms in their children over the year after remission,” the researchers write in the March 15 issue of the American Journal of Psychiatry.