- Overview
- Symptoms
- Causes & Risks
- Diagnosis
- Types
- Major Depressive Disorder
- Treatment
- Antidepressants
- Treatment-Resistant Depression (TRD)
- Living With
- Recovery & Relapse
- Complications
- Caregiving & Support
- Appointment Prep
- View Full Guide
11 Warning Signs of a Depression Relapse
Medically Reviewed by Smitha Bhandari, MD on March 17, 2023
When Depression Comes Back
1/13
More Than "Blue"
2/13
Isolation and Withdrawal
3/13
Sleep Changes
4/13
Irritability
5/13
Can't Enjoy Sex, Fun, or Friends
6/13
Feeling Worthless
7/13
Chronic Aches and Pains
8/13
Sudden Weight Gain or Loss
9/13
Fatigue
10/13
Slowed-Down Thinking
11/13
Suicidal Thoughts
12/13
What You Can Do
13/13