Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Depression Health Center

Font Size

Depression - What Increases Your Risk?

Experts don't know why some people get depression and others don't. But certain things make you likely to get depression. These are called risk factors.

Important risk factors for depression include:

Recommended Related to Depression

Serotonin: 9 Questions and Answers

Serotonin acts as a neurotransmitter, a type of chemical that helps relay signals from one area of the brain to another. Although serotonin is manufactured in the brain, where it performs its primary functions, some 90% of our serotonin supply is found in the digestive tract and in blood platelets.

Read the Serotonin: 9 Questions and Answers article > >

  • Having a father, mother, brother, or sister who has had depression.
  • Having had depression before.
  • Having post-traumatic stress disorder (PTSD).
  • One-time stressful events, such as the death of a loved one, losing your independence or your job, or having a serious accident.

Other risk factors include:

  • Long-term (chronic) stressful situations, such as living in poverty, having marriage or family problems, or helping someone who has a long-term medical problem.
  • Physical or sexual abuse in childhood or in a relationship, such as domestic abuse or violence.
  • Getting older.

Medical risk factors

Medical problems also may cause depression or make it worse. These problems include:

Other risk factors for women

Women have more risk factors. These include:

    WebMD Medical Reference from Healthwise

    Last Updated: November 14, 2014
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
    Next Article:

    Today on WebMD

    Differences between feeling depressed and feeling blue.
    jk rowling
    Famous people who've struggled with persistent sadness.
    depressed man sitting on hallway floor
    Learn the truth about this serious illness.
    Sad woman looking out of the window
    Tips to stay the treatment course.
    unhappy teen boy
    Health Check
    jk rowling
    Pills with smiley faces
    Teen girl huddled outside house
    Depressed man sitting in hospital hallway
    antidepressants slideshow
    pill bottle
    Winding path