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Depression Health Center

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Serotonin Syndrome - Topic Overview

Taking certain medicines together can cause a serious but uncommon condition called serotonin syndrome. Serotonin syndrome can happen when the level of a substance in your brain (called serotonin) gets too high. The problem can happen if you are taking a triptan, used for migraines, along with an antidepressant medicine such as an SSRI or an SNRI. It can also happen if you are taking more than one SSRI or SNRI for depression, anxiety, pain, or another condition.

SSRIs are selective serotonin reuptake inhibitors, and SNRIs are selective serotonin/norepinephrine reuptake inhibitors.

Recommended Related to Depression

Saving Your Sex Life When You're Depressed

Chronic depression affects every part of daily life, including sex. It curbs sex drive, yet sex can boost your mood and is important for relationships. And some depression medicines can curb your libido. Breaking this cycle can be hard. How to get out of this funk? There's no one-size-fits-all approach. But there are some tried-and-true ways to successfully treat depression without ruining your sex life. What’s most important, experts say, is to never stop depression treatment out of fear...

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Symptoms of serotonin syndrome may include:

The best way to prevent serotonin syndrome is to make sure all your doctors know about all of the medicines you are taking. If you are taking a triptan along with an antidepressant (or two antidepressants) and you notice any of these symptoms, call your doctor right away. Without treatment, serotonin syndrome can be deadly. But treatment usually can get rid of the symptoms in less than 24 hours.

WebMD Medical Reference from Healthwise

Last Updated: November 14, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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