Physical pain is a common, but often ignored, symptom of depression. A study published in the journal Psychosomatic Medicine found that two-thirds of people starting treatment for depression also reported being in physical pain. The most commonly cited symptoms were frequent headaches, back pain, joint pain, and abdominal pain.
What's the connection between pain and depression? Research shows that the two share common chemical pathways. The brain chemicals serotonin and norepinephrine are known to play key roles in depression. Now researchers believe these neurotransmitters also mediate pain.