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3. Focus on fat.

In this case, "Fat is good!" Smithson says. To work properly, insulin is supposed to be injected into fatty tissue. The bonus is that getting shots in fleshy sections of your body is less painful than it would be in leaner areas. The stomach, upper arms, thighs, and buttocks all tend to be good spots.

To make shots as painless as possible:

  • Always inject insulin at room temperature.
  • Let the alcohol you use to clean your skin dry so it doesn't burn.
  • Relax the part of your body you're targeting.

You should also insert and remove the needle in a swift, smooth manner without shifting direction, Antinori-Lent says.

If you're still bothered by the prick of the needle, use a cold spoon to numb the area first, says Ghiloni. And it helps to take some deep breaths and calm yourself, especially when you’re new to the process.