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Depression and Diabetes

Depression Treatment With Diabetes continued...

Common side effects of tricyclic antidepressants include:

  • Blurred vision
  • Dry mouth
  • Dizziness
  • Weight gain
  • Constipation
  • Nausea
  • Diarrhea
  • Agitation
  • Insomnia (difficulty falling and staying asleep)
  • Nervousness
  • Headache
  • Changes in sexual desire and/or ability
  • Exhaustion
  • Muscle twitching (tremors)
  • Increased heart rate

Common side effects of SSRI antidepressants include:

  • Nausea
  • Diarrhea
  • Headache
  • Agitation
  • Nervousness
  • Nightmares
  • Dizziness or lightheadedness
  • Changes in sexual desire and/or ability

Common side effects of SNRI antidepressants include

  • Nausea (particularly with Cymbalta)
  • Dry mouth
  • Dizziness
  • Insomnia
  • Sleepiness
  • Constipation
  • Increased blood pressure (with Effexor)
  • Excessive sweating
  • Changes in sexual desire and/or ability


These side effects of antidepressants often go away or become tolerable over time. To minimize the side effects, your doctor may prescribe a small dose of the medication and gradually build up to a higher dose. Side effects also vary with the specific antidepressant used; not every drug causes all of these side effects. Therefore, it may help to change to a different drug that is less likely to cause a particularly uncomfortable side effect if you are having problems.

Counseling, or psychotherapy, is also often beneficial for those suffering from depression. Meeting with a support group can also help.

The Outlook for Depression With Diabetes

The outlook for people with diabetes and depression who seek treatment is very promising. By working with your doctor or a qualified and experienced mental health care professional, you can regain control of your life.




WebMD Medical Reference

Reviewed by Michael Dansinger, MD on September 02, 2014

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People who experience hypoglycemia several times in a week should call their health care provider. It's important to monitor your levels each day so you can make sure your numbers are within the range. If you are pregnant always consult with your health care provider.

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