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What Is Diabetes Insipidus?

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How Is It Treated?

First, the doctor will tell you to drink plenty of fluids. That will replace the constant loss of water.

If you have central diabetes insipidus, there are medications. Vasopressin (Pitressin) or desmopressin (DDAVP) can replace your missing ADH. It usually comes as a nasal spray. There are also treatments that can make these drugs work better.

Nephrogenic diabetes insipidus can be harder to treat. If it’s caused by a drug, stopping the medicine can help. Other medicines may improve the symptoms. These include indomethacin (Indocin), and diuretics like hydrochlorothiazide (Microzide) or amiloride (Moduretic 5-50).

How Serious Is It?

Diabetes insipidus doesn’t cause kidney failure or lead to dialysis. Your kidneys still do their main job, which is to filter your blood.

However, you will be more prone to dehydration. Make sure you always have something to drink close by especially when it’s hot or when you exercise.

WebMD Medical Reference

Reviewed by Michael Dansinger, MD on September 03, 2014
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