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Long-acting insulin can be an important part of your diabetes treatment plan. When taken once a day, long-acting insulin can work all day and all night to help lower your blood sugar.

To understand how long-acting insulin may help, it's important to first understand how insulin works in your body.

How a long-acting insulin like Toujeo® may help

If you aren't hitting your blood sugar goals, ask your doctor if once-daily Toujeo® may be an option for you.

What is Toujeo® (insulin glargine injection) 300 Units/mL?

Prescription Toujeo® is a long-acting insulin used to control blood sugar in adults with diabetes mellitus.

  • Toujeo® contains 3 times as much insulin in 1 mL as standard insulin (100 Units/mL)
  • Toujeo® is not for use to treat diabetic ketoacidosis
  • Toujeo® should not be used in children

Important Safety Information for Toujeo® (insulin glargine injection) 300 Units/mL

Do not take Toujeo® if you have low blood sugar or if you are allergic to insulin or any of the ingredients in Toujeo®.

Important Safety Information | Full Prescribing Information

Why is insulin important?

When we eat, most of the food is broken down into its basic components.
One of them is glucose (sugar), which goes into our bloodstream.

We need insulin to help convert blood sugar into energy that our cells can use.

Healthy Blood Sugar Levels

For people with healthy blood sugar levels (as in the image above), just the right amount of insulin is released from the pancreas to help the body use or store the sugar it gets from food.

Type 2 Diabetes

For people with type 2 diabetes (as in the image above), the pancreas does not produce enough insulin or the body can't properly use the insulin it produces to keep their blood sugar controlled.

If you have type 2 diabetes, your doctor may decide that a long-acting insulin is a good choice for you, depending on your treatment goals.

What does a long-acting insulin need to do?

Remember that long-acting insulin is supposed to cover you in between meals and overnight to help control your blood sugar levels all day and all night. It also should help lower your A1C level to the range you and your doctor decide is right for you.

Working together, you and your doctor will determine whether a long-acting insulin can help you reach your personal treatment goals.

How once-daily Toujeo® may help

Toujeo® is a long-acting insulin that is approved for adults with type 1 and type 2 diabetes who have taken insulin and for those who haven't.

PK graph

Remember your blood sugar levels may vary depending on your diet, physical activity, medicines, and other factors.

The American Diabetes Association (ADA) recommends blood sugar levels to be within ADA target zone (80-130 mg/dL).

Stable blood sugar levels around the clock are just the beginning

A1c=C
  • Proven significant A1C reduction
  • In Toujeo® studies, people with diabetes stopped taking one of their oral pills and still showed significantly lower A1C

    - In clinical trials, patients were required to stop taking sulfonylureas (a kind of oral diabetes medicine).

Toujeo Lantus
  • From the makers of Lantus®, but with a different formulation
  • Releases steadily around the clock with no pronounced peak or wear-off between doses
Guide

Want to ask your doctor about your treatment options?

Guide

Learn more about Toujeo® and why a long-acting insulin may be an option >

Ask your doctor about Toujeo®

Starting on Toujeo®, along with diet and exercise, can be a step that helps you work towards your blood sugar goals.

What is Toujeo® (insulin glargine injection) 300 Units/mL?

Prescription Toujeo® is a long-acting insulin used to control blood sugar in adults with diabetes mellitus.

  • Toujeo® contains 3 times as much insulin in 1 mL as standard insulin (100 Units/mL)
  • Toujeo® is not for use to treat diabetic ketoacidosis
  • Toujeo® should not be used in children

Important Safety Information for Toujeo® (insulin glargine injection) 300 Units/mL

Do not take Toujeo® if you have low blood sugar or if you are allergic to insulin or any of the ingredients in Toujeo®.

Do NOT reuse needles or share insulin pens even if the needle has been changed.

Before starting Toujeo®, tell your doctor about all your medical conditions, including if you have liver or kidney problems, if you are pregnant or planning to become pregnant or if you are breastfeeding or planning to breastfeed.

Heart failure can occur if you are taking insulin together with pills called TZDs (thiazolidinediones), even if you have never had heart failure or other heart problems. If you have heart failure, it may get worse while you take TZDs with Toujeo®. Your treatment with TZDs and Toujeo® may need to be changed or stopped by your doctor if you have new or worsening heart failure. Tell your doctor if you have any new or worsening symptoms, including:

  • Shortness of breath
  • Sudden weight gain
  • Swelling of your ankles or feet

Tell your doctor about all the medications you take, including OTC medicines, vitamins, supplements, and herbal supplements.

Toujeo® should be taken at the same time once a day. Test your blood sugar levels daily while using insulin, including Toujeo®. Do not change your dose or type of insulin without talking to your doctor. Verify that you have the correct insulin before each injection. Do NOT use a syringe to remove TOUJEO® from your SoloStar® pen. Your dose for Toujeo® may be different from other insulins you have taken. Any change of insulin should be made cautiously and only under medical supervision.

Do NOT dilute or mix Toujeo® with any other insulin or solution. It will not work as intended and you may lose blood sugar control, which could be serious. Use Toujeo® only if the solution is clear and colorless with no particles visible.

While using Toujeo®, do not drive or operate heavy machinery until you know how Toujeo® affects you. Don't drink alcohol or use medicines that contain alcohol.

The most common side effect of any insulin, including Toujeo®, is low blood sugar (hypoglycemia), which may be serious and life-threatening. Severe hypoglycemia may cause harm to your heart or brain. Symptoms of serious low blood sugar may include shaking, sweating, fast heartbeat, and blurred vision.

Toujeo® may cause severe allergic reactions that can lead to death. Get medical help right away if you have:

  • A rash over your whole body
  • Shortness of breath
  • Swelling of your face, tongue, or throat
  • Extreme drowsiness, dizziness, or confusion
  • Trouble breathing
  • Fast heartbeat
  • Sweating

Toujeo® may have additional side effects including swelling, weight gain, low potassium, and injection site reactions which may include change in fat tissue, skin thickening, redness, swelling, and itching.

Toujeo® SoloStar® is a disposable prefilled insulin pen. Talk to your doctor about proper injection technique and follow instructions in the Instruction Leaflet that comes with the pen.

Please click here for Full Prescribing Information for Toujeo®. View information on sharps medical waste disposal. Learn about Sanofi's commitment to fighting counterfeit drugs.

If you are a patient experiencing problems with a Sanofi US product, please contact Sanofi US at 1-800-633-1610.

The health information contained herein is provided for general educational purposes only. Your healthcare professional is the single best source of information regarding your health. Please consult your healthcare professional if you have any questions about your health or treatment.

US.GLT.16.08.107

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WebMD does not endorse any specific product, service, or treatment.

From WebMD

More on Diabetes Care

Important Safety Information for Toujeo® (insulin glargine injection) 300 Units/mL

Do not take Toujeo® if you have low blood sugar or if you are allergic to insulin or any of the ingredients in Toujeo®.

Do NOT reuse needles or share insulin pens even if the needle has been changed.