Milk Thistle May Help Treat Diabetes
Iranian Study Shows Improved Blood Sugar Control; Researchers Call for More Studies
WebMD News Archive
Oct. 31, 2006 -- An extract made from milk thistle seeds may help control
blood sugar in people with type 2 diabetes, Iranian researchers say.
But the scientists -- who included H. Fallah Huseini, PhD, of the Institute
of Medicinal Plants in Tehran, Iran -- aren't recommending the extract to
patients just yet.
Instead, they call for further studies to probe milk thistle's effects.
Their report appears online in Phytotherapy Research.
"The results are very encouraging, and now we need to do further large
multi-centre studies," Huseini says in a news release from the journal's
Huseini and colleagues studied 51 adults in Iran with type 2 diabetes.
The patients were 40-60 years old (average age: 53-54) and had had diabetes
for more than two years. Patients took oral diabetes drugs throughout the
The researchers gave the patients tablets to take three times a day with
Half of the patients got tablets containing an extract made from milk
thistle seeds. The others got placebo tablets containing no milk thistle or
Patients didn't know which tablets contained the milk thistle seed
At the study's start, the patients had similar blood sugar levels and blood
But after taking the tablets for four months, the milk thistle group showed
better blood sugar control and cholesterol and triglyceride levels. (Triglyceridesare
a type of blood fat.)
The key might be compounds in milk thistle that are collectively called
silymarin, the researchers say.
"We don't know the exact mechanism of action for this effect, but this
work shows that silymarin could play an important role in treating type 2
diabetes," Huseini says in the news release.
No side effects were reported in this study.
However, milk thistle has been reported to occasionally cause a laxative
effect, upset stomach, diarrhea, bloating, and allergic reactions,
according to the U.S. National Center for Complementary and Alternative
The NCCAM recommends talking with your doctor before you take any herbal or
other dietary supplements.