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As Diabetes Increases, So Does Kidney Disease

Study: Diabetic Kidney Disease Up 34% Since 1988

Diabetes Treatment continued...

For the study, researchers looked at two common measures of kidney disease: albuminuria, or the presence of protein in the urine, and glomerular filtration rate (GFR), which is gauges how quickly the kidneys are able to clean waste out of the blood.

“They’re each a sign of kidney disease. They probably reflect different types of kidney damage,” de Boer says.

Over the two decades covered in this study, de Boer says they saw a shift toward less protein in the urine, but worse GFR, or kidney function.

He says it could be that current diabetes treatments may be lowering protein in the urine while failing to help or perhaps worsening GFR.

“They’re each important manifestations of kidney disease. Each of those signs is bad. They’re both associated with increased risks of cardiovascular disease and increased mortality rates,” he says. “Having either one is bad, and both are worse.”

“This paper shows it’s actually the low GFR side of kidney disease that is most troublesome and increasing,” de Boer says.

The study is published in the Journal of the American Medical Association.

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