Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started
My Medicine

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Diabetes Health Center

Font Size

Prediabetes Linked to Stroke Risk

Lifestyle Changes May Help Prevent Stroke Among People With Prediabetes
WebMD Health News

June 8, 2012 -- People with prediabetes may be at greater risk for stroke, a new study suggests.

Prediabetes refers to blood sugar levels that are higher than normal but not high enough to be defined as having diabetes. This condition places a person at greater risk for full-blown diabetes. Many people with prediabetes also have other risk factors for stroke. These include being overweight or obese, having high blood pressure, and high cholesterol levels.

Researchers from the University of California at San Diego analyzed 15 studies of nearly 761,000 people to get a handle on whether or not prediabetes increases stroke risk.

And it does -- sometimes. Stroke risk varies based on the definition of prediabetes. Not all studies in the new analysis defined prediabetes in the same way.

Prediabetes is typically defined as a fasting (not eating for 12 hours) glucose level between 100 to 125 mg/dl. Seventy to 100 mg/dl is normal.

Studies with people whose blood sugar levels were in the 110 to 125 mg/dl range showed a 21% greater likelihood of stroke. This risk held even after the research team took into account other factors that are known to increase risk for stroke.

This range was how the American Diabetes Association defined prediabetes in 1997. They changed the definition to 100mg/dl to 125mg/dl in 2003.

Studies that used the less-restrictive range did show a higher risk for stroke.

Future stroke risk begins to rise at or above a fasting glucose level of 110 mg/dL, the study authors suggest. Their findings appear in the British Medical Journal.

If you fall into this category, "the best thing you can do is alter your lifestyle," says researcher Bruce Ovbiagele, MD. He is a neuroscientist at University of California at San Diego. "Maintain a normal weight and try to exercise at least three times a week."

There is no medicine that treats prediabetes, but "lifestyle modifications can prevent more than 50% of people from going from prediabetes to frank diabetes, which is a major risk factor for stroke," he says.

The best part is that these lifestyle changes are side-effect free.

"There is a growing epidemic of prediabetes, and more people should check whether or not they have it, regardless of the difference in definitions," Ovbiagele tells WebMD.

Today on WebMD

Diabetic tools
Symptoms, diagnosis, treatment, and more.
woman flexing muscles
10 strength training exercises.
Blood sugar test
12 practical tips.
Tom Hanks
Stars living with type 1 or type 2.
kenneth fujioka, md
Can Vinegar Treat Diabetes
Middle aged person
jennie brand miller

Prediabetes How to Prevent Type 2 Diabetes
type 2 diabetes
food fitness planner