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Diabetes Health Center

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Evidence Weight-Loss Surgery Helps Against Diabetes

One-third of gastric-bypass patients kept type 2 diabetes under control without meds during three-year study


Type 2 diabetes causes the body to use the hormone insulin inefficiently. Insulin helps get sugar from the blood into the body's cells to be used as fuel. When cells become insulin resistant, that fuel can't make it into the cells and instead builds up in the blood. High levels of sugar in the blood over long periods of time can cause serious complications, such as kidney and heart disease, according to the U.S. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

Although the exact cause of type 2 diabetes remains unknown, one of the biggest risk factors for developing the disease is obesity.

The current study included 150 people with type 2 diabetes. Their average age was 49, and two-thirds were female. At the start of the study, the patients' average body-mass index (BMI) -- a rough estimate of a person's body fat -- was nearly 37. Below 25 is considered normal weight and over 30 is considered obese, according to the U.S. Centers for Disease Control and Prevention.

One-third of the study volunteers were randomly selected to receive standard medical management of their type 2 diabetes, while another third was given gastric-bypass surgery and medical management. The final third received sleeve gastrectomy plus medical management of their diabetes.

Gastric-bypass surgery routes food directly to the small intestine, which means it bypasses the stomach, duodenum and large intestines, according to the NIDDK. Sleeve gastrectomy reduces the size of the stomach.

Kashyap said the biggest benefits of the surgeries likely stem from the amount of weight lost. "When you're taking drugs to manage diabetes, it's hard to lose significant amounts of weight," she said. "A lot of diabetes medications make weight loss hard."

Weight-loss surgery costs about $25,000 to $30,000, Kashyap said, and requires about two to four weeks time off of work. Insurance companies generally pay for the procedure only for people who have a BMI over 35, she said.

Because experts at the Cleveland Clinic believe weight-loss surgery can be beneficial for people with lower BMIs who also have other health problems, such as type 2 diabetes, their insurance program pays for the procedure in people with BMIs as low as 30, Kashyap said.

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