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Diabetes and Infections - Topic Overview

High blood sugar from diabetes can affect the body's immune system, impairing the ability of white blood cells to come to the site of an infection, stay in the infected area, and kill microorganisms. Because of the buildup of plaque in blood vessels associated with diabetes, areas of infection may receive a poor blood supply, further lowering the body's ability to fight infections and heal wounds.

Common infections

People with high blood sugar from diabetes can be more severely affected by common infections, such as influenza and pneumonia caused by Streptococcus pneumoniae. This is why immunizations for influenza (the flu) and pneumococcal disease are recommended for people who have diabetes.

And people who have high blood sugar from diabetes are more likely to be infected with unusual organisms, such as Gram-negative bacteria or fungi.

Foot infections

Foot infections are common in people who have high blood sugar from diabetes. Nerve damage (neuropathy) combined with poor blood supply to the feet puts people who have high blood sugar from diabetes at high risk for infected foot ulcers.

Other infections

Other infections for which people with high blood sugar from diabetes are at increased risk include:

  • Yeast infections on the skin and in the urinary tract.
  • Severe infection of the outer ear with the bacteria Pseudomonas aeruginosa. This infection is called malignant external otitis. It causes severe ear pain and drainage from the infected ear.
  • Extremely serious infection of the nose and sinuses with the fungus Rhizopus oryzae. This infection is called zygomycosis or mucormycosis. This is a complication of diabetic ketoacidosis.

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Medical Reference from Healthwise

    Last Updated: July 16, 2013
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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