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Diabetic Nephropathy - Treatment Overview

Ongoing treatment

As diabetic nephropathy progresses, blood pressure usually rises, making it necessary to add more medicine to control blood pressure.

Your doctor may advise you to take the following medicines that lower blood pressure. You may need to take different combinations of these medicines to best control your blood pressure. By lowering your blood pressure, you may reduce your risk of kidney damage. Medicines include:

Continue to avoid other medicines that may damage or stress the kidneys, especially nonsteroidal anti-inflammatory drugs (NSAIDs). And it is still important to keep your blood sugar within your target range, eat healthy foods, get regular exercise, and not smoke.

Treatment if the condition gets worse

If damage to the blood vessels in the kidneys continues, kidney failure may eventually develop. When that occurs, it is likely that you will need dialysis treatment (renal replacement therapy)—an artificial method of filtering the blood—or a kidney transplant to survive. To learn more, see the topic Chronic Kidney Disease.

What to think about

Diabetic nephropathy can get worse during pregnancy and can affect the growth and development of the fetus. If your nephropathy is not severe, your kidney function may return to its prepregnancy level after the baby is born. If you have severe nephropathy, pregnancy may lead to permanent worsening of your kidney function.

If you have nephropathy and are pregnant or are planning to become pregnant, talk with your doctor about which medicines you can take. You may not be able to take some medicines (for example, angiotensin-converting enzyme [ACE] inhibitors or angiotensin II receptor blockers [ARBs]) during pregnancy, because they may harm your developing baby.

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