Medical Dictionary
histoplasmosis
Pronunciation (his′tō-plaz-mō′sis)
- A widely distributed infectious disease caused by Histoplasma capsulatum; occurs occasionally in outbreaks; usually acquired by inhalation of spores of the fungus in soil dust and manifested by a self-limited pneumonia. In patients with emphysema, infection may be chronic and cause pulmonary fibrocavitary disease resembling tuberculosis; in immunosuppressed patients, and rarely, in otherwise healthy persons, histoplasmosis may cause disseminated disease of the reticuloendothelial system, which is manifested by fever, emaciation, splenomegaly, and leukopenia.
Syn: Darling disease
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Stedman’s Medical Dictionary 28th Edition, Copyright© 2006_Lippincott Williams & Wilkins. All rights reserved.



