Medical Dictionary
systemic lupus erythematosus (SLE)
- an inflammatory connective tissue disease with variable features, frequently including fever, weakness and fatigability, joint pains or arthritis resembling rheumatoid arthritis, diffuse erythematous skin lesions on the face, neck, or upper extremities, with liquefaction degeneration of the basal layer and epidermal atrophy, lymphadenopathy, pleurisy or pericarditis, glomerular lesions, anemia, hyperglobulinemia, and a positive LE cell test result, with serum antibodies to nuclear protein and sometimes to double-stranded DNA and other substances.
Syn: disseminated lupus erythematosus
WebMD Medical Reference from "Stedman's Medical Dictionary"
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Stedman’s Medical Dictionary 28th Edition, Copyright© 2006_Lippincott Williams & Wilkins. All rights reserved.



